Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada.
Can J Gastroenterol Hepatol. 2017;2017:6496727. doi: 10.1155/2017/6496727. Epub 2017 Oct 18.
Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life.
Prevalence of anxiety and depression was assessed in IBD outpatients through retrospective chart review. The presence of anxiety and/or depression was determined using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 self-report questionnaires or by diagnosis through psychiatric interview. Patient demographics, disease characteristics, and medication information were also collected. Multivariable analysis was used to determine associations between patient factors and depression and anxiety.
327 patient charts were reviewed. Rates of depression and anxiety were found to be 25.8% and 21.2%, with 30.3% of patients suffering from depression and/or anxiety. Disease activity was found to be significantly associated with depression and/or anxiety ( = 0.01). Females were more likely to have anxiety ( = 0.01).
A significant proportion of IBD patients suffer from depression and/or anxiety. The rates of these mental illnesses would justify screening and referral for psychiatric treatment in clinics treating this population. Patients with active disease are particularly at risk for anxiety and depression.
尽管人们知道慢性疾病患者中抑郁和焦虑的患病率较高，且其对生活质量有负面影响，但炎症性肠病（IBD）患者并未常规筛查抑郁和焦虑。
通过回顾性病历审查评估 IBD 门诊患者的焦虑和抑郁患病率。使用患者健康问卷-9 和广泛性焦虑障碍-7 自评问卷或通过精神病学访谈进行诊断来确定是否存在焦虑和/或抑郁。还收集了患者人口统计学、疾病特征和药物信息。采用多变量分析来确定患者因素与抑郁和焦虑之间的关联。
共回顾了 327 份患者病历。抑郁和焦虑的发生率分别为 25.8%和 21.2%，有 30.3%的患者患有抑郁和/或焦虑。疾病活动度与抑郁和/或焦虑显著相关（ = 0.01）。女性更容易出现焦虑（ = 0.01）。
相当一部分 IBD 患者患有抑郁和/或焦虑。这些精神疾病的发生率表明，在治疗此类人群的诊所中，进行筛查和转介接受精神科治疗是合理的。患有活动期疾病的患者尤其容易出现焦虑和抑郁。
