Kubo S
Nagasaki University School of Medicine, Japan.
J Forensic Sci. 1989 Jan;34(1):96-104.
Three strains of Cunninghamella elegance (C. elegance), Penicillium simplicissimum (P. simpl.), and Aspergillus niger (A. niger) were isolated from soil that produced the enzymes acting on blood groups A and B red cells. Culture filtrates from these fungi contained alpha-N-acetyl-D-galactosaminidase as an A-decomposing enzyme, which resulted in an almost complete loss of A specificity and an enhancement of blood group H activity as measured by elution tests using monoclonal antibodies. They also contained an alpha-D-galactosidase and an alpha-L-fucosidase, which partially destroyed the blood group B specific activity, but did not influence the blood group H specific activity.
从土壤中分离出了三株雅致小克银汉霉（C. elegance）、简单青霉（P. simpl.）和黑曲霉（A. niger），它们能产生作用于A和B血型红细胞的酶。这些真菌的培养滤液含有α-N-乙酰-D-半乳糖胺酶作为一种分解A的酶，通过使用单克隆抗体的洗脱试验测量，这导致A特异性几乎完全丧失，血型H活性增强。它们还含有α-D-半乳糖苷酶和α-L-岩藻糖苷酶，这两种酶部分破坏了B血型的特异性活性，但不影响血型H的特异性活性。
