Relland Lance M, Tobias Joseph D, Martin David, Veneziano Giorgio, Beltran Ralph J, McKee Christopher, Bhalla Tarun
Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital.
Department of Anesthesiology and Pain Medicine, The Ohio State University College of Medicine.
J Pain Res. 2017 Nov 9;10:2629-2634. doi: 10.2147/JPR.S144259. eCollection 2017.
Umbilical hernia repair is a common pediatric surgical procedure. While opioid analgesics are a feasible option and have long been a mainstay in the pharmacological intervention for pain, the effort to improve care and limit opioid-related adverse effects has led to the use of alternative techniques, including regional anesthesia. The current study prospectively compares the analgesic efficacy of three techniques, including caudal epidural blockade, peripheral nerve blockade, and local wound infiltration, in a double-blinded study.
A total of 39 patients undergoing umbilical hernia repair were randomized to receive a caudal epidural block (CDL), ultrasound-guided bilateral rectus sheath blocks (RSB), or surgical site infiltration (SSI) with local anesthetic. Intraoperative anesthetic care was standardized, and treatment groups were otherwise blinded from the intraoperative anesthesiology team and recovery nurses. Postoperatively, the efficacy was evaluated using Hannallah pain scores, Aldrete recovery scores, the need for intravenous fentanyl, and the time to discharge.
Each cohort was similar in terms of age, weight, premedication dosing, length of case, intraoperative and postoperative fentanyl requirements, and time to tracheal extubation. Among the three cohorts, there were no significant differences noted in terms of pain scores or time to recovery.
All the three techniques provided effective analgesia following umbilical hernia repair. Our findings offer effective and safe analgesic options as alternatives to the neuraxial (caudal) approach.
脐疝修补术是一种常见的儿科外科手术。虽然阿片类镇痛药是一种可行的选择,并且长期以来一直是疼痛药物干预的主要手段,但为改善护理并限制阿片类药物相关不良反应所做的努力促使人们采用包括区域麻醉在内的替代技术。本研究在一项双盲研究中前瞻性地比较了三种技术的镇痛效果,这三种技术包括骶管硬膜外阻滞、外周神经阻滞和局部伤口浸润。
共有39例接受脐疝修补术的患者被随机分配接受骶管硬膜外阻滞(CDL)、超声引导下双侧腹直肌鞘阻滞(RSB)或局部麻醉药手术部位浸润(SSI)。术中麻醉护理标准化,治疗组对术中麻醉团队和恢复室护士保持盲态。术后,使用汉纳拉疼痛评分、阿尔德雷特恢复评分、静脉注射芬太尼的需求以及出院时间来评估疗效。
各队列在年龄、体重、术前用药剂量、手术时长、术中和术后芬太尼需求量以及气管拔管时间方面相似。在三个队列中,疼痛评分或恢复时间方面均未观察到显著差异。
这三种技术在脐疝修补术后均提供了有效的镇痛效果。我们的研究结果提供了有效且安全的镇痛选择,可作为椎管内(骶管)方法的替代方案。