竖脊肌平面阻滞与骶管阻滞用于小儿腹股沟疝修补术后镇痛的随机对照试验。

Erector spinae plane block versus caudal block for postoperative analgesia in pediatric patients undergoing inguinal hernia repair: a randomized controlled trial.

机构信息

Department of Anesthesiology, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.

Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, People's Republic of China.

出版信息

Ann Med. 2023;55(2):2298868. doi: 10.1080/07853890.2023.2298868. Epub 2023 Dec 28.

Abstract

BACKGROUND

Erector spinae plane block is a promising strategy for pain management in some settings. However, the effectiveness of erector spinae plane block versus caudal block in pediatric inguinal hernia repair has yet to be formally investigated.

METHODS

One hundred and two patients aged 2-5 years undergoing unilateral open inguinal hernia repair randomly received unilateral erector spinae plane block (0.2% ropivacaine 0.5 mL kg), caudal block (0.2% ropivacaine 1 mL kg), or no block. The primary outcome was time to the first rescue analgesia, defined as the interval from the end of surgery to the Face, Legs, Activity, Cry, and Consolability scale greater than three. Secondary outcomes included the number of patients requiring rescue analgesia, the area under the curve of pain scores over time, satisfaction of guardians, and adverse events.

RESULTS

The median time to the first rescue analgesia was longer in the erector spinae plane block group than in the caudal block group [10.0 h (interquartile range, 6.6-24.0 h) vs. 5.0 h (interquartile range, 2.9-7.3 h);  < .001]. The Cox regression model demonstrated that the risk of postoperative rescue analgesia requirement was 0.38 in children receiving erector spinae plane block compared with caudal block (95% confidence interval 0.23-0.64;  < .001). Additionally, the area under the curve of the pain scores over time was lower in the erector spinae plane block group than in the caudal block group (44.3 [36.6-50.7] vs. 59.0 [47.1-64.5];  < .001).

CONCLUSIONS

Erector spinae plane block provided superior postoperative analgesia compared to caudal block in children undergoing inguinal hernia repair.: Chinese Clinical Trial Registry; ChiCTR2100048303.

摘要

背景

竖脊肌平面阻滞在某些情况下是一种有前途的疼痛管理策略。然而,在小儿腹股沟疝修补术中,竖脊肌平面阻滞与骶管阻滞的效果尚未得到正式研究。

方法

102 例 2-5 岁接受单侧开放式腹股沟疝修补术的患者随机接受单侧竖脊肌平面阻滞(0.2%罗哌卡因 0.5ml/kg)、骶管阻滞(0.2%罗哌卡因 1ml/kg)或无阻滞。主要结局是首次补救镇痛的时间,定义为手术结束至面部、腿部、活动、哭泣和安慰程度评分大于 3 的间隔时间。次要结局包括需要补救镇痛的患者人数、疼痛评分随时间的曲线下面积、监护人满意度和不良事件。

结果

竖脊肌平面阻滞组的首次补救镇痛时间中位数长于骶管阻滞组[10.0h(四分位距,6.6-24.0h)比 5.0h(四分位距,2.9-7.3h);  < .001]。Cox 回归模型显示,与骶管阻滞相比,接受竖脊肌平面阻滞的患儿术后需要补救镇痛的风险为 0.38(95%置信区间 0.23-0.64;  < .001)。此外,竖脊肌平面阻滞组的疼痛评分随时间的曲线下面积低于骶管阻滞组(44.3[36.6-50.7]比 59.0[47.1-64.5];  < .001)。

结论

在接受腹股沟疝修补术的儿童中,与骶管阻滞相比,竖脊肌平面阻滞提供了更好的术后镇痛效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ae4/10763821/8f4e61c539c7/IANN_A_2298868_F0001_C.jpg

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