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早期直肠癌的局部切除与内镜切除术

Local Excision and Endoscopic Resections for Early Rectal Cancer.

作者信息

São Julião Guilherme Pagin, Celentano Juan Pablo, Alexandre Flavia Andrea, Vailati Bruna Borba

机构信息

Angelita & Joaquim Gama Institute, São Paulo, São Paulo, Brazil.

出版信息

Clin Colon Rectal Surg. 2017 Nov;30(5):313-323. doi: 10.1055/s-0037-1606108. Epub 2017 Nov 27.

Abstract

Radical surgery is considered as the standard treatment for rectal cancer. Transanal local excision has been considered an interesting alternative for the management of selected patients with rectal cancers for many decades. Different approaches had been considered for local excision, from endoscopic submucosal dissection to resections using platforms, such as transanal endoscopic microsurgery or transanal minimally invasive surgery. Identifying the ideal candidate for this approach is crucial, as a local failure after local excision is associated with poor outcomes, even for an initial early rectal tumor. In this article, the diagnostic tools and criteria to select patients for local excision, the different modalities used, and the outcomes are discussed.

摘要

根治性手术被认为是直肠癌的标准治疗方法。几十年来,经肛门局部切除术一直被视为治疗部分直肠癌患者的一种有吸引力的替代方法。局部切除曾考虑过不同的方法,从内镜黏膜下剥离术到使用诸如经肛门内镜显微手术或经肛门微创手术等平台进行的切除术。确定这种方法的理想候选者至关重要,因为局部切除术后的局部失败与不良预后相关,即使对于最初的早期直肠肿瘤也是如此。本文讨论了选择局部切除患者的诊断工具和标准、所使用的不同方式以及治疗结果。

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