用于监测多发性硬化症残疾状况的可穿戴生物传感器。
Wearable biosensors to monitor disability in multiple sclerosis.
作者信息
Bradshaw Michael J, Farrow Samantha, Motl Robert W, Chitnis Tanuja
机构信息
Department of Neurology (MJB), Vanderbilt University Medical Center, Nashville, TN; Wentworth Biotechnology (SF), NC; Department of Physical Therapy (RWM), University of Alabama at Birmingham; and Partners Multiple Sclerosis Center (TC, MJB, SF, TC), Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
出版信息
Neurol Clin Pract. 2017 Aug;7(4):354-362. doi: 10.1212/CPJ.0000000000000382.
PURPOSE OF REVIEW
Biosensors capable of measuring physiologic and kinetic parameters associated with disability are being applied to the study of people with multiple sclerosis (MS). We review the use of biosensors in people with MS with an emphasis on measuring/monitoring disability and understanding knowledge gaps between biosensor data and clinical care.
RECENT FINDINGS
Accelerometers are available to the public and may be able to help the clinician understand a patient's degree of disability. Further studies with wearable biosensors capable of measuring other physiologic features, such as vital signs, are needed and are likely to contribute to our understanding of MS.
SUMMARY
Wearable biosensors can improve our understanding of disability, response to treatment, and natural history of MS.
综述目的
能够测量与残疾相关的生理和动力学参数的生物传感器正被应用于多发性硬化症（MS）患者的研究。我们回顾生物传感器在MS患者中的应用，重点是测量/监测残疾情况以及了解生物传感器数据与临床护理之间的知识差距。
最新发现
加速度计已向公众提供，可能有助于临床医生了解患者的残疾程度。需要对能够测量其他生理特征（如生命体征）的可穿戴生物传感器进行进一步研究，这可能有助于我们对MS的理解。
总结
可穿戴生物传感器可以提高我们对MS患者残疾情况、治疗反应和自然病史的理解。
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