Miao Ailiang, Wang Xiaoshan
1 Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
2 Department of Video-Electroencephalography, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Clin EEG Neurosci. 2018 Sep;49(5):302-305. doi: 10.1177/1550059417745185. Epub 2017 Nov 30.
Previous studies have shown that extreme delta brush and high beta/delta power ratio on electroencephalogram are suggestive of anti- N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis. Here we report 3 anti-NMDAR encephalitis patients with ictal rhythmic alpha sinusoidal waves in temporal regions, which suggested electrographic seizures in anti-NMDAR encephalitis and indicated potential for seizure occurrence in the future. Rhythmic alpha sinusoidal waves may be an electrographic feature and helpful in distinguishing anti-NMDAR encephalitis. In addition, extreme delta brush was also observed at 47-50 days after morbidity in 2 of 3 patients.
先前的研究表明，脑电图上的极端δ波刷和高β/δ功率比提示抗N-甲基-D-天冬氨酸受体（抗NMDAR）脑炎。在此，我们报告3例抗NMDAR脑炎患者，其颞区出现发作期节律性α正弦波，提示抗NMDAR脑炎存在脑电图痫样放电，并预示未来有发作可能。节律性α正弦波可能是一种脑电图特征，有助于鉴别抗NMDAR脑炎。此外，3例患者中有2例在发病后47 - 50天也观察到了极端δ波刷。
