Hayashi Shizuka, Tanaka Tomohisa, Moriishi Kohji, Hirayama Kazuhiro, Yamada Akio, Hotta Kozue
Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Department of Microbiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, Japan.
J Vet Med Sci. 2018 Feb 2;80(1):186-189. doi: 10.1292/jvms.17-0527. Epub 2017 Nov 29.
Non-primate hepacivirus (NPHV) is recently identified as a closely related homologue of hepatitis C virus. The previous studies showed a high prevalence of NPHV infection among Japanese domestic horses originated from abroad. The historical distribution of NPHV among horses in Japan, therefore, is still unknown. In this study, seroepidemiological study of NPHV was conducted using 335 sera from five breeds of Japanese native horses. These horses are maintained as the pedigree and are reared apart from other horse breeds. The detection of antibodies against NPHV were conducted by western blot analysis using the recombinant protein of the NPHV core protein. The antibodies against NPHV were detected in all five breeds, 83 out of 335 (23.4%) horses. These results suggested that NPHV was circulating among Japanese native horses.
非灵长类丙型肝炎病毒（NPHV）最近被鉴定为丙型肝炎病毒的密切相关同源物。先前的研究表明，在来自国外的日本国产马中，NPHV感染率很高。因此，NPHV在日本马匹中的历史分布仍然未知。在本研究中，使用来自五个日本本土马品种的335份血清进行了NPHV的血清流行病学研究。这些马作为纯种马饲养，与其他马品种分开饲养。使用NPHV核心蛋白的重组蛋白通过western blot分析检测抗NPHV抗体。在所有五个品种的335匹马中有83匹（23.4%）检测到抗NPHV抗体。这些结果表明NPHV在日本本土马中传播。
Zotero 插件