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通过激光诱导击穿光谱法对甲状腺进行元素分析。

Elemental analysis of the thyroid by laser induced breakdown spectroscopy.

作者信息

Ahmed Irfan, Ahmed Rafay, Yang Jingwei, Law Alan Wing Lun, Zhang Yanpeng, Lau Condon

机构信息

Department of Physics, City University of Hong Kong, Hong Kong SAR, China.

Department of Electrical Engineering, Sukkur IBA University, Sukkur 65200, Pakistan.

出版信息

Biomed Opt Express. 2017 Oct 6;8(11):4865-4871. doi: 10.1364/BOE.8.004865. eCollection 2017 Nov 1.

Abstract

The thyroid is an important hormone regulation organ. Laser induced breakdown spectroscopy (LIBS) is developed to assess iodine and other essential elements in the thyroid (of rats). Subjects are administered 0.05% iodine water for 0, 6, and 12 days before the thyroid is extracted. Pronounced iodine, sodium, calcium, and potassium emissions are observed at approximately 746, 589, 395/422, and 766/770 nm, respectively. Iodine emission is surprisingly highest in 0 day subjects, lowest after 6 days, and recovers by 12 days. This follows the Wolff-Chaikoff effect as ingestion of excess iodine reduces thyroid iodine and iodine is essential for hormone production. LIBS is a promising method for trace elemental analysis of the thyroid.

摘要

甲状腺是一个重要的激素调节器官。激光诱导击穿光谱法(LIBS)被开发用于评估(大鼠)甲状腺中的碘及其他必需元素。在提取甲状腺之前,给实验对象分别在0天、6天和12天给予0.05%的碘水。在大约746nm、589nm、395/422nm和766/770nm处分别观察到明显的碘、钠、钙和钾发射谱线。碘发射谱线在0天的实验对象中出奇地最高,6天后最低,到12天恢复。这符合Wolff-Chaikoff效应,即摄入过量碘会减少甲状腺中的碘,而碘对于激素产生至关重要。LIBS是一种用于甲状腺微量元素分析的有前景的方法。

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本文引用的文献

1
In situ cellular level Raman spectroscopy of the thyroid.甲状腺的原位细胞水平拉曼光谱分析
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Consequences of excess iodine.碘过量的后果。
Nat Rev Endocrinol. 2014 Mar;10(3):136-42. doi: 10.1038/nrendo.2013.251. Epub 2013 Dec 17.

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