Department of Psychiatry, Hyvinkää Hospital Area, Hospital District of Helsinki and Uusimaa, Hyvinkää, Finland.
Alcohol, Drugs and Addictions Unit, Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.
Qual Life Res. 2018 May;27(5):1217-1226. doi: 10.1007/s11136-017-1741-z. Epub 2017 Nov 29.
To compare the associations of alcohol-related variables with Quality of Life (QoL) in depressed and non-depressed individuals of the general population.
This cross-sectional study utilized data from the FINRISK 2007 general population survey. A subsample (n = 4020) was invited to participate in an interview concerning alcohol use. Of them, 2215 (1028 men, 1187 women; response rate 55.1%) were included in the analyses. Bivariate associations between mean weekly alcohol consumption, frequency of binge drinking, Alcohol Use Disorders Identification Test (AUDIT)-score and QoL were analysed according to categorization into depressed and non-depressed using the Beck Depression Inventory, Short Form. Linear regression models were calculated in order to determine the associations of the alcohol variables and QoL after adjusting for socio-demographic variables as well as somatic and mental illness.
Depressed individuals had lower mean QoL and higher AUDIT-scores than non-depressed respondents. Bivariate correlations showed that mean weekly alcohol consumption, frequency of binge drinking and AUDIT-scores were statistically significantly associated with impaired QoL in depressed individuals. Abstinence was not associated with QoL. After adjustment for covariates, frequency of binge drinking and AUDIT-score were statistically significantly associated with QoL in depressed individuals and AUDIT-score in the non-depressed group. When analysing all respondents regardless of depression, both AUDIT-score and binge drinking were associated with QoL.
Of the alcohol-related variables, binge drinking and alcohol problems indicated by AUDIT-score contributed to impaired QoL in depressed individuals and both should be assessed as part of the clinical management of depression.
比较与酒精相关的变量与抑郁和非抑郁人群生活质量(QoL)之间的关联。
本横断面研究利用了 FINRISK 2007 年一般人群调查的数据。邀请一个子样本(n=4020)参加关于饮酒使用的访谈。其中,2215 人(1028 名男性,1187 名女性;应答率为 55.1%)被纳入分析。根据贝克抑郁量表将平均每周酒精摄入量、 binge drinking 频率、酒精使用障碍识别测试(AUDIT)评分与 QoL 进行分类,分析它们与抑郁和非抑郁人群之间的关系。采用线性回归模型,以确定在调整社会人口统计学变量以及躯体和精神疾病后,酒精变量与 QoL 的关系。
与非抑郁组相比,抑郁组的平均 QoL 较低,AUDIT 评分较高。双变量相关性显示,平均每周酒精摄入量、 binge drinking 频率和 AUDIT 评分与抑郁个体的 QoL 受损呈统计学显著相关。戒酒与 QoL 无关。在调整了协变量后, binge drinking 频率和 AUDIT 评分与抑郁个体的 QoL 以及非抑郁组的 AUDIT 评分呈统计学显著相关。在分析所有不论抑郁与否的受访者时,AUDIT 评分和 binge drinking 都与 QoL 相关。
在与酒精相关的变量中, binge drinking 和 AUDIT 评分所示的酒精问题与抑郁个体的 QoL 受损有关,在抑郁的临床管理中,两者都应该进行评估。