Das Sumit, Ang Lee-Cyn, Ramsay David
Clin Neuropathol. 2018 Mar/Apr;37(2):64-67. doi: 10.5414/NP301012.
Cavernous hemangioma in the sellar region is quite rare with only a handful of cases being reported in the English literature. Its clinical manifestations and imaging characteristics can mimic those of a pituitary adenoma. We report two cases of recurrent sellar lesions, both of which were clinically suspected of being pituitary adenomas but histologically confirmed as cavernous hemangiomas. The first case is of a 67-year-old female whose initial resection was diagnosed as "venous angioma". Neuroimaging performed 27 years later demonstrated significant growth of the lesion involving the right cavernous sinus and encasing the right internal carotid artery. The patient then underwent transsphenoidal endoscopic resection of the mass. At the time of the surgery, the lesion was noted to be quite vascular. The second case is a 48-year-old female who underwent emergency resection of a pituitary mass following an apoplectic event. On follow-up 4 years later, the patient reported recurrence of galactorrhea, and MRI had demonstrated regrowth of the mass. She subsequently underwent subtotal resection of the mass. At the time of surgery, brisk bleeding was noted in the operative area. The above two cases demonstrate that cavernous hemangiomas in the sellar region can clinically and radiologically mimic pituitary adenoma and should be considered in the differential diagnosis of hemorrhagic sellar mass. .
鞍区海绵状血管瘤相当罕见,英文文献中仅报道过少数病例。其临床表现和影像学特征可与垂体腺瘤相似。我们报告两例复发性鞍区病变,两例临床上均怀疑为垂体腺瘤,但组织学确诊为海绵状血管瘤。第一例为67岁女性,其初次切除术后诊断为“静脉血管瘤”。27年后的神经影像学检查显示病变显著生长,累及右侧海绵窦并包绕右侧颈内动脉。该患者随后接受了经蝶窦内镜下肿物切除术。手术时,发现病变血管丰富。第二例为48岁女性,在一次卒中样发作后接受了垂体肿物急诊切除术。4年后随访时,患者报告出现溢乳复发,MRI显示肿物再次生长。她随后接受了肿物次全切除术。手术时,发现手术区域出血活跃。上述两例表明,鞍区海绵状血管瘤在临床和影像学上可与垂体腺瘤相似,在出血性鞍区肿物的鉴别诊断中应予以考虑。