From the Center for Vaccines and Immunity.
Biostatistics Core, The Research Institute at Nationwide Children's Hospital, Columbus, OH.
Pediatr Infect Dis J. 2018 Jun;37(6):514-519. doi: 10.1097/INF.0000000000001836.
Admission criteria and standardized management strategies for bronchiolitis are addressed in several guidelines and have shown to be beneficial; however, guidance regarding discharge criteria is limited and widely variable. We assessed the impact on clinical outcomes of a discharge protocol for children <2 years of age hospitalized with bronchiolitis in a tertiary care pediatric hospital.
In October 2013, a protocol to standardize the discharge of children with bronchiolitis was implemented in the infectious diseases (ID) ward but not in other pediatric units caring for these children (non-ID). The protocol included objective clinical criteria and a standardized oxygen weaning pathway. Patients were identified via International Classification of Diseases-9 codes and data manually reviewed. We compared length of stay (LOS) and readmission rates within 2 weeks of discharge according to protocol implementation (ID versus non-ID), adjusted for demographic factors, comorbidities, viral etiology and stratified by pediatric intensive care unit admission.
From October 2013 to May 2015, 1118 children were hospitalized in ID and 695 in non-ID units. Median age was 4.5 months, 55% were males and 28% had comorbidities. LOS was 36% longer in non-ID units (risk ratio: 1.36 [1.27-1.45]; P < 0.001) adjusted for age, gender, comorbidities and viral etiology. Difference in LOS remained significant after excluding children with comorbidities and stratifying by pediatric intensive care unit admission. Readmission rates were comparable between units (ID, 2.9% versus non-ID, 2.6%).
A standardized discharge protocol for bronchiolitis reduced LOS without increasing readmission rates. Unifying bronchiolitis discharge criteria and oxygen weaning pathways could positively impact hospital-based patient care for this condition.
几项指南都提到了毛细支气管炎的入院标准和规范化管理策略,这些策略已被证明是有益的;然而,关于出院标准的指导意见有限且差异很大。我们评估了在一家三级儿科医院的传染病病房中为毛细支气管炎住院的<2 岁儿童实施出院方案对临床结局的影响。
2013 年 10 月,在传染病病房实施了一项标准化毛细支气管炎患儿出院方案,但其他儿科病房(非传染病病房)不实施。该方案包括客观临床标准和标准化的氧疗撤机途径。通过国际疾病分类第 9 版(ICD-9)代码识别患者,并手动审查数据。根据方案实施情况(传染病病房与非传染病病房),我们比较了出院后 2 周内的住院时间(LOS)和再入院率,并根据人口统计学因素、合并症、病毒病因进行了调整,并按小儿重症监护病房(PICU)入院情况进行了分层。
2013 年 10 月至 2015 年 5 月,共有 1118 名儿童在传染病病房住院,695 名儿童在非传染病病房住院。中位年龄为 4.5 个月,55%为男性,28%有合并症。非传染病病房的 LOS 长 36%(风险比:1.36[1.27-1.45];P<0.001),调整了年龄、性别、合并症和病毒病因后差异仍有统计学意义。排除合并症的儿童后,差异仍然显著,并按 PICU 入院情况进行了分层。两个病房的再入院率相似(传染病病房为 2.9%,非传染病病房为 2.6%)。
毛细支气管炎标准化出院方案可降低 LOS,而不增加再入院率。统一毛细支气管炎的出院标准和氧疗撤机途径可以对该疾病的住院患者护理产生积极影响。