Morgan C M, Schatz H
Vitreoretinal Service, W.K. Kellogg Eye Center, University of Michigan Medical Center, Ann Arbor.
Ophthalmology. 1989 Jan;96(1):96-103. doi: 10.1016/s0161-6420(89)32924-1.
To determine if enlargement of laser scars occurs in nonmyopic individuals, the authors retrospectively reviewed 126 consecutive patients with age-related macular degeneration who had been successfully treated with focal macular laser photocoagulation for subretinal neovascularization. Of the 174 laser scars in the study, 122 (70%) increased in size from 50 to 1016 microns (mean, 290 microns) as determined photographically on serial examination ranging from 2 to 81 months. There was no statistically significant difference in the number of scars which increased in size among the three laser wavelengths used. Four (3%) patients lost vision as a result of the scar extending into the fovea. Enlargement of retinal pigment epithelial (RPE) atrophy after focal macular laser photocoagulation may cause significant, delayed visual loss after successful treatment of subretinal neovascularization.
为了确定非近视个体中激光瘢痕是否会扩大，作者回顾性分析了126例年龄相关性黄斑变性患者，这些患者均因视网膜下新生血管化而成功接受了黄斑区局灶性激光光凝治疗。在该研究的174处激光瘢痕中，根据连续2至81个月的系列检查照片测定，122处（70%）瘢痕大小从50微米增加到1016微米（平均290微米）。所使用的三种激光波长中，瘢痕增大的数量在统计学上无显著差异。4例（3%）患者因瘢痕延伸至黄斑中心凹而视力丧失。黄斑区局灶性激光光凝后视网膜色素上皮（RPE）萎缩扩大，可能在成功治疗视网膜下新生血管化后导致显著的、延迟性视力丧失。
