Pineda-Galindo Luis Francisco, Vera-Lastra Olga Lidia, Carrazco-Ibarra Lucía, Carrasco-Gómez Alejandra, Becerril-Ángeles Martín, Ramos-Salazar Patricia, Martínez-Solano Jaime
Hospital de Especialidades "Dr. Antonio Fraga Mouret", Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México
Rev Med Inst Mex Seguro Soc. 2017 Nov-Dec;55(6):796-800.
IgG4-related disease is an inflammatory condition characterized by high levels of IgG4. It affects salivary and lacrimal glands, pancreas, lymph nodes, lungs or kidney. The diagnosis is based on identifying a histological pattern with a dense lymphocyte and plasmacyte infiltration, focal fibrosis or phlebitis, finding more than 10 IgG4 positive cells per high power field and/or IgG4/IgG ratio in plasma higher than 40%. We present a patient with Mikulicz's disease who meets histological findings required for the diagnosis of IgG4 related disease.
IgG4相关性疾病是一种以IgG4水平升高为特征的炎症性疾病。它会影响唾液腺、泪腺、胰腺、淋巴结、肺或肾脏。诊断基于识别一种具有密集淋巴细胞和浆细胞浸润、局灶性纤维化或静脉炎的组织学模式，在每个高倍视野中发现超过10个IgG4阳性细胞和/或血浆中IgG4/IgG比率高于40%。我们报告了一例符合IgG4相关性疾病诊断所需组织学表现的米库利奇病患者。
