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相对腰椎前凸和前凸分布指数:基于个体化骨盆入射角的比例参数,比骨盆入射角减去腰椎前凸的概念更精确地量化腰椎前凸。

Relative lumbar lordosis and lordosis distribution index: individualized pelvic incidence-based proportional parameters that quantify lumbar lordosis more precisely than the concept of pelvic incidence minus lumbar lordosis.

机构信息

Department of Orthopedics and Traumatology, Acibadem Mehmet Ali Aydinlar University School of Medicine.

Comprehensive Spine Center, Acibadem Maslak Hospital, Istanbul.

出版信息

Neurosurg Focus. 2017 Dec;43(6):E5. doi: 10.3171/2017.8.FOCUS17498.

Abstract

OBJECTIVE The subtraction of lumbar lordosis (LL) from the pelvic incidence (PI) offers an estimate of the LL required for a given PI value. Relative LL (RLL) and the lordosis distribution index (LDI) are PI-based individualized measures. RLL quantifies the magnitude of lordosis relative to the ideal lordosis as defined by the magnitude of PI. LDI defines the magnitude of lower arc lordosis in proportion to total lordosis. The aim of this study was to compare RLL and PI - LL for their ability to predict postoperative complications and their correlations with health-related quality of life (HRQOL) scores. METHODS Inclusion criteria were ≥ 4 levels of fusion and ≥ 2 years of follow-up. Mechanical complications were proximal junctional kyphosis/proximal junctional failure, distal junctional kyphosis/distal junctional failure, rod breakage, and implant-related complications. Correlations between PI - LL, RLL, PI, and HRQOL were analyzed using the Pearson correlation coefficient. Mechanical complication rates in PI - LL, RLL, LDI, RLL, and LDI interpreted together, and RLL subgroups for each PI - LL category were compared using chi-square tests and the exact test. Predictive models for mechanical complications with RLL and PI - LL were analyzed using binomial logistic regressions. RESULTS Two hundred twenty-two patients (168 women, 54 men) were included. The mean age was 52.2 ± 19.3 years (range 18-84 years). The mean follow-up was 28.8 ± 8.2 months (range 24-62 months). There was a significant correlation between PI - LL and PI (r = 0.441, p < 0.001), threatening the use of PI - LL to quantify spinopelvic mismatch for different PI values. RLL was not correlated with PI (r = -0.093, p > 0.05); therefore, it was able to quantify divergence from ideal lordosis for all PI values. Compared with PI - LL, RLL had stronger correlations with HRQOL scores (p < 0.05). Discrimination performance was better for the model with RLL than for PI - LL. The agreement between RLL and PI - LL was high (κ = 0.943, p < 0.001), moderate (κ = 0.455, p < 0.001), and poor (κ = -0.154, p = 0.343), respectively, for large, average, and small PI sizes. When analyzed by RLL, each PI - LL category was further divided into distinct groups of patients who had different mechanical complication rates (p < 0.001). CONCLUSIONS Using the formula of PI - LL may be insufficient to quantify normolordosis for the whole spectrum of PI values when applied as an absolute numeric value in conjunction with previously reported population-based average thresholds of 10° and 20°. Schwab PI - LL groups were found to constitute an inhomogeneous group of patients. RLL offers an individualized quantification of LL for all PI sizes. Compared with PI - LL, RLL showed a greater association with both mechanical complications and HRQOL. The use of RLL and LDI together, instead of PI - LL, for surgical planning may result in lower mechanical complication rates and better long-term HRQOL.

摘要

目的

腰椎前凸(LL)从骨盆入射角(PI)中减去,可估算给定 PI 值所需的 LL。相对 LL(RLL)和脊柱前凸分布指数(LDI)是基于 PI 的个体化测量指标。RLL 定量测量相对于理想 LL 的 LL 幅度,该幅度由 PI 的幅度定义。LDI 定义了总 LL 中下段弧 LL 的幅度。本研究旨在比较 RLL 和 PI-LL 对术后并发症的预测能力及其与健康相关生活质量(HRQOL)评分的相关性。

方法

纳入标准为融合≥4 个节段,随访时间≥2 年。机械性并发症包括近端交界性后凸/近端交界性失败、远端交界性后凸/远端交界性失败、杆断裂和植入物相关并发症。使用 Pearson 相关系数分析 PI-LL、RLL、PI 和 HRQOL 之间的相关性。使用卡方检验和确切检验比较 PI-LL、RLL、LDI、RLL 和 LDI 综合解释中的机械并发症发生率,以及每个 PI-LL 类别的 RLL 亚组。使用二项逻辑回归分析 RLL 和 PI-LL 对机械并发症的预测模型。

结果

共纳入 222 例患者(女性 168 例,男性 54 例)。平均年龄为 52.2±19.3 岁(18-84 岁)。平均随访时间为 28.8±8.2 个月(24-62 个月)。PI-LL 与 PI 之间存在显著相关性(r=0.441,p<0.001),这威胁到使用 PI-LL 来量化不同 PI 值的脊柱骨盆不匹配。RLL 与 PI 无相关性(r=-0.093,p>0.05);因此,它能够定量测量所有 PI 值的理想脊柱前凸偏差。与 PI-LL 相比,RLL 与 HRQOL 评分的相关性更强(p<0.05)。RLL 的判别性能优于 PI-LL。RLL 与 PI-LL 之间的一致性较高(κ=0.943,p<0.001),中等(κ=0.455,p<0.001),低(κ=-0.154,p=0.343),分别为大、中、小 PI 尺寸。当通过 RLL 进行分析时,每个 PI-LL 类别进一步分为具有不同机械并发症发生率的不同患者亚组(p<0.001)。

结论

当作为与先前报道的基于人群的 10°和 20°平均阈值相结合的绝对值使用时,PI-LL 公式可能不足以量化整个 PI 值范围内的正常脊柱前凸。Schwab PI-LL 组被发现是一组异质患者。RLL 为所有 PI 尺寸提供了个体化的 LL 定量测量。与 PI-LL 相比,RLL 与机械并发症和 HRQOL 均具有更强的相关性。与 PI-LL 相比,使用 RLL 和 LDI 进行手术规划可能会降低机械并发症发生率并改善长期 HRQOL。

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