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相对骨盆倾斜度:一种基于个体化骨盆入射角的比例参数,比骨盆倾斜度更精确地量化骨盆倾斜度。

Relative pelvic version: an individualized pelvic incidence-based proportional parameter that quantifies pelvic version more precisely than pelvic tilt.

机构信息

Department of Orthopedics and Traumatology, Acibadem Mehmet Ali Aydinlar University, Kayisdagi Caddesi 32, Istanbul, 34752, Turkey.

Department of Biostatistics, Ankara University, Adnan Saygun Caddesi, Ankara, 06230, Turkey.

出版信息

Spine J. 2018 Oct;18(10):1787-1797. doi: 10.1016/j.spinee.2018.03.001. Epub 2018 Mar 8.

Abstract

BACKGROUND CONTEXT

Pelvic tilt (PT) is used as an indicator of pelvic version with increased values indicating retroversion and disability. The concept of using PT solely as an absolute numerical value can be misleading, especially for the patients with pelvic incidence (PI) values near the upper and lower normal limits. Relative pelvic version (RPV) is a PI-based individualized measure of the pelvic version. Relative pelvic version indicates the individualized spatial orientation of the pelvis relative to the ideal sacral slope as defined by the magnitude of PI.

PURPOSE

The aim of this study was to compare RPV and PT for their ability to predict mechanical complications and their correlations with health-related quality of Life (HRQoL) scores.

STUDY DESIGN

A retrospective analysis of a prospectively collected data of adult spinal deformity patients was carried out. Mechanical complications (proximal junctional kyphosis or proximal junctional failure, distal junctional kyphosis or distal junctional failure, rod breakage, and implant-related complications) and HRQoL scores (Oswestry Disability Index [ODI], Core Outcome Measures Index [COMI], Short Form-36 Physical Component Summary [SF-36 PCS], and Scoliosis Research Society 22 Spinal Deformity Questionnaire [SRS-22]) were used as outcome measures.

METHODS

Inclusion criteria were ≥4 levels fusion, and ≥2-year follow-up. Correlations between PT, RPV, PI, and HRQoL were analyzed using Pearson correlation coefficient. Pelvic incidence values and mechanical complication rates in RPV subgroups for each PT category were compared using one-way analysis of variance, Student t test, and chi-squared tests. Predictive models for mechanical complications with RPV and PT were analyzed using binomial logistic regressions.

RESULTS

A total of 222 patients (168 women, 54 men) met the inclusion criteria. Mean age was 52.2±19.3 (18-84) years. Mean follow-up was 28.8±8.2 (24-62) months. There was a significant correlation between PT and PI (r=0.613, p<.001), threatening the use of PT to quantify pelvic version for different PI values. Relative pelvic version was not correlated with PI (r=-0.108, p>.05), being able to quantify pelvic version for all PI values. Compared with PT, RPV had stronger partial correlations with ODI, COMI, SF-36 PCS, and SRS-22 scores (p<.05). Discrimination performance assessed by area under the curve, percentage accuracy in classification, true positive rate, true negative rate, and positive and negative predictive values was better for the model with RPV than for PT. For average PI sizes, the agreement between RPV and PT were moderate (0.609, p<.001), whereas the agreement in small and large PI sizes were poor (0.189, p>.05; -0.098, p>.496, respectively). When analyzed by RPV, each PT "0," "+," and "++" category was further divided into two or three distinct subgroups of patients having different PI values (p=.000, p=.000, and p=.029, respectively). Relative pelvic version subgroups within the same PT category displayed different mechanical complication rates (p=.000, p=.020, and p=.019, respectively).

CONCLUSIONS

Pelvic tilt may be insufficient or misleading in quantifying normoversion for the whole spectrum of PI values when used as an absolute numeric value in conjunction with previously reported population-based average thresholds of 20 and 30 degrees. Relative pelvic version offers an individualized quantification of ante-, normo-, and retroversion for all PI sizes. Schwab PT groups were found to constitute inhomogeneous subgroup of patients with different mean PI values and mechanical complication rates. Compared with PT, RPV showed a greater association with both mechanical complications and HRQoL.

摘要

背景语境

骨盆倾斜度(PT)用于指示骨盆倾斜度,增加的值表示后倾和功能障碍。当与之前报道的基于人群的 20 度和 30 度平均阈值结合使用时,仅将 PT 作为绝对数值可能会产生误导,特别是对于骨盆入射角(PI)值接近上下正常范围的患者。相对骨盆版本(RPV)是基于 PI 的骨盆倾斜度的个体化测量。相对骨盆版本表示骨盆相对于理想骶骨斜率的个体化空间方位,该方位由 PI 的大小定义。

目的

本研究的目的是比较 RPV 和 PT 预测机械并发症的能力及其与健康相关生活质量(HRQoL)评分的相关性。

研究设计

对前瞻性收集的成年脊柱畸形患者数据进行回顾性分析。机械并发症(近端交界性后凸或近端交界性失败、远端交界性后凸或远端交界性失败、棒断裂和植入物相关并发症)和 HRQoL 评分(Oswestry 残疾指数[ODI]、核心结果测量指标指数[COMI]、简化 36 项健康调查[SF-36 PCS]和脊柱侧凸研究协会 22 项脊柱畸形问卷[SRS-22])作为结局指标。

方法

纳入标准为≥4 个节段融合和≥2 年随访。使用 Pearson 相关系数分析 PT、RPV、PI 和 HRQoL 之间的相关性。使用单因素方差分析、学生 t 检验和卡方检验比较每个 PT 类别中 RPV 亚组的 PI 值和机械并发症发生率。使用二项逻辑回归分析 RPV 和 PT 预测机械并发症的预测模型。

结果

共纳入 222 名患者(168 名女性,54 名男性),平均年龄为 52.2±19.3(18-84)岁,平均随访时间为 28.8±8.2(24-62)个月。PT 与 PI 呈显著相关(r=0.613,p<.001),这威胁到使用 PT 来量化不同 PI 值的骨盆倾斜度。RPV 与 PI 无相关性(r=-0.108,p>.05),能够量化所有 PI 值的骨盆倾斜度。与 PT 相比,RPV 与 ODI、COMI、SF-36 PCS 和 SRS-22 评分的部分相关性更强(p<.05)。曲线下面积、分类准确率、真阳性率、真阴性率、阳性和阴性预测值评估的判别性能,RPV 模型优于 PT 模型。对于平均 PI 大小,RPV 与 PT 的一致性为中度(0.609,p<.001),而在小和大 PI 大小的一致性较差(0.189,p>.05;-0.098,p>.496,分别)。当按 RPV 分析时,每个 PT“0”、“+”和“++”类别进一步分为具有不同 PI 值的两个或三个不同亚组的患者(p=.000,p=.000 和 p=.029,分别)。同一 PT 类别内的 RPV 亚组显示出不同的机械并发症发生率(p=.000,p=.020 和 p=.019,分别)。

结论

当与之前报道的基于人群的 20 度和 30 度平均阈值结合使用时,PT 作为绝对数值可能会产生误导,无法充分或准确地量化整个 PI 值范围内的正常前倾。相对骨盆版本为所有 PI 大小提供了一种个体化的前、中、后倾的量化方法。施瓦布 PT 组被发现构成了具有不同平均 PI 值和机械并发症发生率的异质患者亚组。与 PT 相比,RPV 与机械并发症和 HRQoL 均具有更大的相关性。

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