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STRIPP 问卷(用于银屑病患者风湿性疾病筛查的工具)作为一种新的早期银屑病关节炎诊断工具。

The STRIPP questionnaire (Screening Tool for Rheumatologic Investigation in Psoriatic Patients) as a new tool for the diagnosis of early psoriatic arthritis.

机构信息

Section of Dermatology, Department of Health Sciences (DISSAL), IRCCS San Martino University Hospital, Genoa, Italy -

Section of Dermatology, Department of Health Sciences (DISSAL), IRCCS San Martino University Hospital, Genoa, Italy.

出版信息

G Ital Dermatol Venereol. 2020 Jun;155(3):294-298. doi: 10.23736/S0392-0488.17.05745-5. Epub 2017 Nov 30.

Abstract

BACKGROUND

Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis in up to one third of psoriatic patients. Clinically it's characterized from an insidious onset. To help clinicians screen for PsA, several screening tools have been developed. The psoriatic arthritis screening and evaluation questionnaire (PASE) is one of the most used in the Psocare units. The sensibility of PASE is of 83% with a cut off of 47 or greater. The aim of our study is to create an Italian self-administered questionnaire, lighter than the PASE, able to identify patients who need a rheumatologic consultation.

METHODS

Between April and June 2016 an Italian group of dermatologists and rheumatologists from north Italy developed a new questionnaire called Screening Tool for Rheumatologic Investigation in Psoriatic Patient (STRIPP). Two hundred and twelve patients with the diagnosis of psoriasis, were screened with STRIPP by dermatologists and all of them sent to the rheumatologist.

RESULTS

Forty seven out of 212 patients received the diagnosis of early psoriatic arthritis. Statistical analysis (Spearman Rank correlation Test, Mann Whitney Test) showed a specificity of 93.3% and a sensibility of 91.5% taking a point of 3.5 as a cut-off.

CONCLUSIONS

The STRIPP is a very easy questionnaire, quick to fill out and has a very high sensitivity and specificity, higher than the PASE. Our future goal will be to screen more patients for validating the STRIPP questionnaire.

摘要

背景

银屑病关节炎(PsA)是一种炎症性关节炎,在多达三分之一的银屑病患者中伴发银屑病。临床上,它以隐匿性发病为特征。为帮助临床医生筛查银屑病关节炎,已经开发出几种筛查工具。银屑病关节炎筛查和评估问卷(PASE)是 Psocare 单位中使用最多的问卷之一。PASE 的敏感性为 83%,截断值为 47 或更高。我们研究的目的是创建一个比 PASE 更轻的意大利语自填问卷,以识别需要风湿病咨询的患者。

方法

2016 年 4 月至 6 月,意大利北部的一组皮肤科医生和风湿病学家开发了一种名为“银屑病患者风湿病调查筛查工具(STRIPP)”的新问卷。212 名银屑病患者由皮肤科医生用 STRIPP 进行筛查,所有患者均被转诊给风湿病医生。

结果

212 名患者中有 47 名被诊断为早期银屑病关节炎。统计分析(Spearman 秩相关检验,Mann-Whitney 检验)显示,以 3.5 分为截断值时,特异性为 93.3%,敏感性为 91.5%。

结论

STRIPP 是一种非常简单的问卷,填写迅速,具有很高的敏感性和特异性,高于 PASE。我们的未来目标将是筛查更多的患者来验证 STRIPP 问卷。

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