Hioki Tomoyuki, Komine Mayumi, Ohtsuki Mamitaro
Department of Dermatology, Central Japan International Medical Center, Minokamo 505-8510, Japan.
Department of Dermatology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke 329-0498, Japan.
J Clin Med. 2022 Apr 6;11(7):2051. doi: 10.3390/jcm11072051.
Psoriatic arthritis (PsA) is a chronic inflammatory disorder that affects approximately 20-30% of patients with psoriasis. PsA causes deformities and joint damage, impairing quality of life and causing long-term functional disability. Several recent studies demonstrated that early diagnosis and intervention for PsA prevents permanent invalidity. However, the clinical features of PsA vary and are shared with other differential diseases, such as reactive arthritis, osteoarthritis, and ankylosing spondylitis. The common and overlapping features among these diseases complicate the accurate early diagnosis and intervention of PsA. Therefore, this review focuses on the current knowledge of the diagnosis of early PsA and discusses the meaning of early intervention for early PsA.
银屑病关节炎（PsA）是一种慢性炎症性疾病，影响约20%-30%的银屑病患者。PsA会导致畸形和关节损伤，损害生活质量并造成长期功能残疾。最近的几项研究表明，对PsA进行早期诊断和干预可预防永久性残疾。然而，PsA的临床特征各不相同，且与其他鉴别疾病（如反应性关节炎、骨关节炎和强直性脊柱炎）有共同之处。这些疾病之间常见且重叠的特征使PsA的准确早期诊断和干预变得复杂。因此，本综述重点关注早期PsA诊断的当前知识，并讨论早期干预对早期PsA的意义。
