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银屑病关节炎:皮肤科医生的全面更新及文献综述

Psoriatic Arthritis: A Comprehensive Update for Dermatologists with Review of Literature.

作者信息

Datta Debatri, Podder Indrashis, De Abhishek, Das Sudip

机构信息

Consultant Dermatologist, Oliva Skin Clinic, Kolkata, West Bengal, India.

Department of Dermatology, Venereology and Leprosy, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.

出版信息

Indian J Dermatol. 2022 Jul-Aug;67(4):381-386. doi: 10.4103/ijd.ijd_571_22.

Abstract

Psoriatic arthritis (PsA), an inflammatory seronegative spondyloarthropathy is the most common co-morbidity of psoriasis (PsO), in almost 30% of cases. Delayed diagnosis and treatment of PsA may result in irreversible joint damage, significant morbidity, impaired quality of life, and several cardiometabolic and cerebrovascular co-morbidities. Dermatologists are uniquely privileged to be able to diagnose latent PsA at an early stage, as almost 80% of these patients present with pre-existing cutaneous PsO. This review provides a detailed overview of PsA along with its salient clinical features, classification criteria, screening tools, simple physical examination maneuvers, imaging findings, and therapeutic options to acquaint dermatologists and other clinicians with this morbid musculoskeletal disorder. We hope to generate awareness about this condition among dermatologists to enable proactive screening of all PsO patients for early diagnosis, initiation of appropriate treatment, and prompt referral to a rheumatologist; thus, helping to arrest PsA disease progression, irreversible joint damage, and subsequent permanent disability.

摘要

银屑病关节炎(PsA)是一种炎症性血清阴性脊柱关节炎,是银屑病(PsO)最常见的合并症,几乎见于30%的病例。PsA诊断和治疗的延迟可能导致不可逆转的关节损伤、严重的发病率、生活质量受损以及多种心脏代谢和脑血管合并症。皮肤科医生具有独特的优势,能够在早期诊断潜在的PsA,因为几乎80%的此类患者已有皮肤PsO。本综述详细概述了PsA及其显著的临床特征、分类标准、筛查工具、简单的体格检查方法、影像学表现和治疗选择,以使皮肤科医生和其他临床医生了解这种病态的肌肉骨骼疾病。我们希望提高皮肤科医生对这种疾病的认识,以便对所有PsO患者进行主动筛查,实现早期诊断、开始适当治疗并及时转诊给风湿病学家;从而有助于阻止PsA疾病进展、不可逆转的关节损伤和随后的永久性残疾。

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