Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
University of Chinese Academy of Sciences, Beijing, China.
Eur J Immunol. 2018 Feb;48(2):384-385. doi: 10.1002/eji.201747284.
Gradual depletion of CD4 T cells is a typical characteristic of pathogenic SIV infection. Intriguingly, we find a spontaneous CD4 T-cell homeostasis in northern pig-tailed macaques (Macaca leonina) during SIVmac239 infection.
CD4 T 细胞的逐渐耗竭是致病性 SIV 感染的典型特征。有趣的是,我们在感染 SIVmac239 的北方长尾猕猴(Macaca leonina)中发现了自发的 CD4 T 细胞动态平衡。