Byard Roger W
School of Medicine, The University of Adelaide, Frome Road, Adelaide, SA, 5005, Australia.
J Forensic Sci. 2018 Jul;63(4):1312-1315. doi: 10.1111/1556-4029.13709. Epub 2017 Nov 28.
Rates of syphilis are beginning to once again increase, with the World Health Organization estimating that in recent years there were 12 million new cases of syphilis each year; in 2002, syphilis was responsible for 0.3% of deaths globally. At-risk groups include young males (20-29 years), prisoners, and sex workers. Increased rates in young females have elevated the numbers of congenital cases. Review of the University of Adelaide Pathology Archive revealed four cases with significant pathology, which included cardiac gummas and aortic arch aneurysms. These cases demonstrate the cardiovascular characteristics of untreated syphilis in the tertiary stage. Cases with such advanced pathology will only occur where diagnoses have not been made, and/or standard antibiotic therapy has not been implemented in the early stage of disease.
梅毒发病率正再次开始上升，世界卫生组织估计近年来每年有1200万新梅毒病例；2002年，梅毒导致全球0.3%的死亡。高危人群包括年轻男性（20 - 29岁）、囚犯和性工作者。年轻女性发病率的上升增加了先天性梅毒病例的数量。对阿德莱德大学病理学档案的回顾发现了4例有显著病理变化的病例，其中包括心脏树胶样肿和主动脉弓动脉瘤。这些病例展示了三期未经治疗梅毒的心血管特征。只有在未做出诊断和/或疾病早期未实施标准抗生素治疗的情况下才会出现如此严重病理变化的病例。
