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[病毒性或细菌性脑膜炎。鉴别诊断问题]

[Viral or bacterial meningitis. Differential diagnostic problems].

作者信息

Aukrust P, Haugtomt H

出版信息

Tidsskr Nor Laegeforen. 1989 Feb 10;109(4):448-50.

PMID:2919375
Abstract

A 19 year old previously healthy man presented symptoms of meningitis. Culture from the cerebrospinal fluid revealed herpes simplex virus type 2 to be the responsible agent. The course was benign, the patient was never seriously ill. He recovered fully within a few weeks. The cerebrospinal fluid showed prolonged pleocytosis and low values of glucose. The traditional cerebrospinal fluid parameters employed in the diagnosis of meningitis, and for distinguishing bacterial from viral meningitis, are shown to be inadequate in many cases. Of these tests cerebrospinal fluid differential cell count is of most value, especially if repeated after 12 hours or so in the initial course. Additional tests have been proposed, none of which have proven to be of much help, except perhaps the test for lactate in the cerebrospinal fluid.

摘要

一名19岁既往健康的男性出现了脑膜炎症状。脑脊液培养显示2型单纯疱疹病毒是致病原。病程呈良性,患者从未病情严重。他在几周内完全康复。脑脊液显示淋巴细胞增多持续时间长且葡萄糖值低。用于脑膜炎诊断以及区分细菌性脑膜炎和病毒性脑膜炎的传统脑脊液参数在许多情况下被证明是不够的。在这些检查中,脑脊液细胞分类计数最有价值,尤其是在病程初期约12小时后重复检测时。已经提出了其他检查方法,但除了脑脊液乳酸检测外,没有一种被证明有很大帮助。

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