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精神分裂症谱系障碍患者的特征、住院时间和功能改善:2005 年至 2015 年安大略省住院治疗的人群研究。

Patient Characteristics, Length of Stay, and Functional Improvement for Schizophrenia Spectrum Disorders: A Population Study of Inpatient Care in Ontario 2005 to 2015.

机构信息

1 Centre for Addiction and Mental Health, Toronto, Ontario.

2 Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario.

出版信息

Can J Psychiatry. 2017 Dec;62(12):854-863. doi: 10.1177/0706743716680167. Epub 2016 Dec 14.

Abstract

OBJECTIVES

Schizophrenia and associated illnesses account for a large proportion of mental illness burden and health care expenditures, with the majority of expense involving inpatient care. To date, the literature exploring factors associated with length of stay (LOS) and functional improvement during inpatient care is underdeveloped. In response, this study examined the association between patient characteristics, LOS, and functional improvement using Ontario Mental Health Reporting System (OMHRS) data from 2005 to 2015.

METHODS

The associations of patient characteristics (including key demographics, psychosocial variables, reasons for admission, and service use history) and 2 outcome measures (LOS and Global Assessment of Functioning [GAF]) were analysed with generalised linear mixed modelling (GLMM). From 2005 to 2015, a total of 48,498 episodes for distinct patients from 18 psychiatric hospitals and 57 general hospitals in Ontario were included.

RESULTS

For psychiatric and general hospitals, mean LOS was 96.6 and 20.5 days, and mean GAF improvement was 14.8 and 16.1, respectively. The majority of associations probed demonstrated a high degree of significance with similar patterns across general and tertiary facility contexts. Older age and more recent readmission following a psychiatric discharge were associated with longer LOS and less GAF improvement. Recent experience of adverse life events and substance misuse were associated with shorter LOS.

CONCLUSIONS

While the findings of this exploratory cross-sectional analysis will require further inquiry with respect to validity and reliability, they suggest that a different service pathway is likely required for individuals with greater psychosocial challenge and extensive service use histories.

摘要

目的

精神分裂症及相关疾病在精神疾病负担和医疗保健支出中占很大比例,其中大部分费用涉及住院治疗。迄今为止,有关与住院期间住院时间(LOS)和功能改善相关的因素的文献研究还不够发达。有鉴于此,本研究使用 2005 年至 2015 年安大略省心理健康报告系统(OMHRS)的数据,研究了患者特征、住院时间和功能改善之间的关系。

方法

使用广义线性混合模型(GLMM)分析了患者特征(包括关键人口统计学,心理社会变量,入院原因和服务使用史)与 2 个结局指标(住院时间和总体评估功能[GAF])的关联。从 2005 年至 2015 年,共纳入了来自安大略省 18 家精神病院和 57 家综合医院的 48498 例不同患者的发作情况。

结果

对于精神病院和综合医院,平均住院时间分别为 96.6 和 20.5 天,平均 GAF 改善分别为 14.8 和 16.1。探查的大多数关联都具有高度显著性,并且在一般和三级医疗机构的情况下具有相似的模式。年龄较大以及精神病院出院后最近再次入院与住院时间延长和 GAF 改善减少有关。近期经历不良生活事件和物质滥用与较短的住院时间有关。

结论

尽管这项探索性横断面分析的结果需要进一步进行有效性和可靠性研究,但它们表明,对于具有更大心理社会挑战和广泛服务使用史的个体,可能需要不同的服务途径。

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