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精神分裂症和分裂情感性障碍:住院时长及相关因素。

Schizophrenia and schizoaffective disorder: Length of stay and associated factors.

作者信息

Goga Ladawa Y, Marais Belinda S

机构信息

Department of Psychiatry, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

出版信息

S Afr J Psychiatr. 2024 Apr 22;30:2237. doi: 10.4102/sajpsychiatry.v30i0.2237. eCollection 2024.

Abstract

BACKGROUND

Patients with schizophrenia and schizoaffective disorder often require longer admissions.

AIM

To explore length of stay (LOS) and associated factors of patients with schizophrenia and schizoaffective disorder, admitted to a public sector specialised psychiatric hospital, over a 4-year period.

SETTING

The study was conducted at Tara Hospital in Johannesburg.

METHODS

A retrospective record review of 367 adult schizophrenia and schizoaffective disorder patients admitted between 01 January 2015 and 31 December 2018. Average LOS was calculated and the proportion of short-stay (< 30 days), medium-stay (31-90 days) and long-stay (> 90 days) admissions determined. Sociodemographic, clinical and admission outcome data were collected and analysed from a randomly selected subset of patients in each LOS category.

RESULTS

Mean LOS was 128 days (median 87, interquartile range [IQR] 49-164, range 0-755 days). A significantly greater proportion had long-stay admissions ( < 0.001). Male gender ( = 0.018), being unmarried ( = 0.006), treatment resistant ( < 0.001) and on clozapine ( = 0.009) were factors found to have a significant association with long-stay admissions. Rates of unemployment (> 80%), comorbid substance use disorders (> 40%), medical illnesses (> 40%), antipsychotic polypharmacy (> 40%) and readmissions (> 80%) were high. Most (> 80%) were discharged.

CONCLUSION

Long-stay admissions were frequently required for patients with schizophrenia and schizoaffective disorder admitted to Tara Hospital.

CONTRIBUTION

This study highlights factors associated with long-stay admissions in patients with schizophrenia and schizoaffective disorder. More research is needed into whether increased access to community-based services, such as residential and daycare facilities, outpatient substance rehabilitation programmes and dual diagnosis clinics, could translate into shorter admissions, less frequent relapses and improved outcomes in this population.

摘要

背景

精神分裂症和分裂情感性障碍患者通常需要更长的住院时间。

目的

探讨在4年期间入住一家公共部门专业精神病医院的精神分裂症和分裂情感性障碍患者的住院时间(LOS)及相关因素。

地点

该研究在约翰内斯堡的塔拉医院进行。

方法

对2015年1月1日至2018年12月31日期间收治的367例成年精神分裂症和分裂情感性障碍患者进行回顾性病历审查。计算平均住院时间,并确定短期住院(<30天)、中期住院(31 - 90天)和长期住院(>90天)患者的比例。从每个住院时间类别中随机选择的患者子集中收集并分析社会人口统计学、临床和出院结局数据。

结果

平均住院时间为128天(中位数87天,四分位间距[IQR]49 - 164天,范围0 - 755天)。长期住院患者的比例显著更高(<0.001)。发现男性(=0.018)、未婚(=0.006)、难治性(<0.001)和使用氯氮平(=0.009)与长期住院显著相关。失业率(>80%)、合并物质使用障碍(>40%)、内科疾病(>40%)、抗精神病药物联合使用(>40%)和再入院率(>80%)都很高。大多数(>80%)患者出院。

结论

入住塔拉医院的精神分裂症和分裂情感性障碍患者经常需要长期住院。

贡献

本研究突出了精神分裂症和分裂情感性障碍患者长期住院的相关因素。对于增加获得社区服务(如住宿和日间护理设施、门诊物质康复项目和双重诊断诊所)是否能转化为该人群更短的住院时间、更少的复发次数和更好的结局,还需要更多研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9c/11079426/d300bceaf7bf/SAJPsy-30-2237-g001.jpg

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