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儿童和青少年特发性颅内高压:更新。

Idiopathic Intracranial Hypertension in Children and Adolescents: An Update.

机构信息

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA.

出版信息

Headache. 2018 Mar;58(3):485-493. doi: 10.1111/head.13236. Epub 2017 Dec 1.

Abstract

PREMISE

Idiopathic intracranial hypertension (IIH), previously known as pseudotumor cerebri syndrome (PTC) is a serious neurological disorder that can lead to irreversible visual loss. Predominantly a disorder affecting women in reproductive years, the pediatric population is not spared.

PROBLEM

In the past few years, the condition has been redefined, due to new accepted values for opening pressure in children and advances in neuroimaging. Emerging techniques in ophthalmology are being increasingly used to monitor disease in these patients. And, although the treatment tools have not changed in several years, important evidence for efficacy for acetazolamide finally came to light in recent years in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT).

POTENTIAL SOLUTION

This review article provides an overview on recent advances in diagnosis, evaluation and treatment of IIH.

摘要

前提

特发性颅内高压(IIH),以前称为假性脑瘤综合征(PTC),是一种严重的神经系统疾病,可导致不可逆转的视力丧失。这种疾病主要影响生育期的女性,但儿童也无法幸免。

问题

由于儿童颅内压正常值的新接受值和神经影像学的进步,这种情况在过去几年中得到了重新定义。眼科新兴技术越来越多地用于监测这些患者的疾病。而且,尽管治疗方法在几年内没有改变,但最近几年,特发性颅内高压治疗试验(IIHTT)终于为乙酰唑胺的疗效提供了重要证据。

潜在解决方案

本文综述了 IIH 的诊断、评估和治疗的最新进展。

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