Bredesen J, Madsen M, Andersen T F, Loft A, Roepstorff C, Jørgensen T
Ugeskr Laeger. 1989 Feb 13;151(7):426-30.
In a register-based study of all cholecystectomized patients in Denmark during the period from 1977-85 (37,048 patients) an account is given of the regional variations observed in connection with the intervention. The cholecystectomy operation is sub-divided into four types of operation dependent on whether the intervention is merely a matter of cholecystectomy or it involves the choledocus, the duodenum, the small intestine or other organs. The variation analysis is based on a division of the country into 75 areas, each primarily served by a single hospital. The method highly reflects the differences in clinical treatment strategies. The summarized rate of cholecystectomy for this period of time was 8.2 per 10,000 persons. In areas with the highest and the lowest rates of operation the figures were 12.3 per 10,000 and 5.1 per 10,000, respectively. In 18 areas, the rates of operation were significantly higher than average and in 18 other areas significantly higher than average and in 18 other areas significantly below average. SCV-score (X100) 2.19. There is no systematic correlation between the degree of specialisation in the operating department and the frequency in employing the operation. Areas with an operation index significantly above average had the same rate of more complicated operations than simple cholecystectomy as the other areas. Possible causes of national as well as international variations in the use of cholecystectomy are discussed, and the need for a radical evaluation of this kind of treatment is emphasized.
在一项基于丹麦1977 - 1985年期间所有接受胆囊切除术患者(37,048例)登记资料的研究中,报告了与该手术相关的区域差异情况。根据手术干预仅仅是胆囊切除术,还是涉及胆总管、十二指肠、小肠或其他器官,将胆囊切除术细分为四种手术类型。差异分析基于将该国划分为75个区域,每个区域主要由一家医院服务。该方法高度反映了临床治疗策略的差异。这段时间内胆囊切除术的汇总发生率为每10,000人中有8.2例。手术发生率最高和最低的区域,相应数字分别为每10,000人中有12.3例和5.1例。在18个区域,手术发生率显著高于平均水平,在另外18个区域显著低于平均水平。标准化系数值(×100)为2.19。手术科室的专业化程度与手术使用频率之间没有系统的相关性。手术指数显著高于平均水平的区域,其复杂手术(相对于单纯胆囊切除术)的发生率与其他区域相同。讨论了胆囊切除术在国内以及国际上使用差异的可能原因,并强调了对这种治疗方法进行彻底评估的必要性。