Simons Foundation Autism Research Initiative, Simons Foundation,New York, New York 10010.
Cold Spring Harb Perspect Biol. 2017 Dec 1;9(12):a032904. doi: 10.1101/cshperspect.a032904.
Scientists who leave the laboratory bench to work for biomedical foundations mobilize and focus resources on the most promising research behind a foundation's mission. They acquire a broad view of a field, interact closely with research scientists at meetings and laboratory visits, and often manage proposal review boards and monitor grant progress. Increasingly, scientists at foundations also have a more active role in catalyzing research: They are involved in organizing targeted workshops, setting research priorities, and directly creating and managing resources for a scientific community. They often work closely with patient advocacy groups, contract research organizations, government funders and regulators, and biotech and pharmaceutical companies.Job opportunities in foundations are highly varied, reflecting the diversity of foundations and missions. For example, some foundations have general missions to support broad basic scientific research, whereas others focus specifically on a particular disease and may require different skills. Most scientific positions at foundations require a PhD or MD and often some postdoctoral or other experience, although not all do. Foundations often lack the clear career path that an academic position offers (various levels of professorship, tenure, etc.), although there is often significant potential for growth in responsibilities in terms of managing science, people, and budgets. Jobs in foundations can be challenging yet extremely rewarding, especially for those with broad interests and goal-oriented personalities. Many at foundations feel that they have the potential to have an even greater impact than if they had stayed at the bench.
离开实验室转而在生物医药基金会工作的科学家们会调动并集中资源在基金会使命背后最有前途的研究上。他们会对一个领域有更广泛的了解,在会议和实验室访问中与研究科学家密切互动,并且经常管理提案审查委员会和监测资助进展。越来越多的基金会科学家也在促进研究方面发挥着更积极的作用:他们参与组织有针对性的研讨会,确定研究重点,并直接为科学界创建和管理资源。他们经常与患者权益团体、合同研究组织、政府资助者和监管机构以及生物技术和制药公司密切合作。基金会的工作机会多种多样,反映了基金会和使命的多样性。例如,一些基金会的总体使命是支持广泛的基础科学研究,而其他基金会则专门针对特定疾病,可能需要不同的技能。大多数基金会的科学职位都需要博士或医学博士学位,并且通常需要一些博士后或其他经验,尽管并非所有职位都需要。基金会通常缺乏学术职位所提供的明确职业道路(教授的各个级别、终身职位等),尽管在管理科学、人员和预算方面,通常有很大的责任增长潜力。基金会的工作可能具有挑战性,但也非常有回报,特别是对于那些兴趣广泛、目标明确的人来说。许多在基金会工作的人都觉得他们有可能比留在实验室时产生更大的影响。