Leaw Bryan, Gurusinghe Seshini, Lim Rebecca, Wallace Euan M
Hudson Institute of Medical Research, Clayton, VIC, 3168, Australia.
Maternal Fetal Medicine Unit, Department of Obstetrics & Gynaecology, Monash Medical Centre, Monash Health & Monash University, 246 Clayton Road, Clayton, VIC, 3168, Australia.
Methods Mol Biol. 2018;1710:325-334. doi: 10.1007/978-1-4939-7498-6_26.
Radiotelemetry is increasingly being recognized not just as the gold standard but a necessity for validation of gestational hypertension seen in preeclampsia. Here we describe radiotelemetry probe implantation into the descending aorta of Sprague-Dawley rats to allow real-time blood pressure recording over the entire gestational period. This is a valuable tool to be able to track changes in maternal blood pressure throughout gestation and the efficacy of novel therapeutic agents in controlling hypertension.
无线电遥测技术不仅越来越被视为金标准，而且对于子痫前期中出现的妊娠高血压的验证也是必不可少的。在此，我们描述了将无线电遥测探头植入Sprague-Dawley大鼠的降主动脉，以便在整个妊娠期进行实时血压记录。这是一种能够追踪整个妊娠期母体血压变化以及新型治疗药物控制高血压疗效的宝贵工具。
