Indrapriyadharshini K, Madankumar P D, Karthikeyan G R
Department of Public Health Dentistry, Ragas Dental College and Hospital, Chennai, India.
Department of Oral and Maxillofacial Surgery, Karpaga Vinayaga Institute of Dental Sciences, Kanchipuram, Tamil Nadu, India.
Indian J Cancer. 2017 Jan-Mar;54(1):11-15. doi: 10.4103/ijc.IJC_116_17.
The modern-day onco-surgical therapy is now concerned on the overall Quality of Life after treatment of the patient. There is need to evaluate final outcome following the different combination of treatment modalities available to make better therapeutic treatment decisions.
The aim of this study was to assess Oral health related quality of life (OHRQoL) in patients with oral malignancies who had undergone various treatments.
A Cross sectional study was conducted among 90 patients between October 2016 to January 2017 in private hospitals, kanchipuram, India.
Participants were grouped based on the treatment they had undergone into Group I - Surgery alone, Group II - Surgery and Radiotherapy, Group III- Surgery, chemotherapy and radiotherapy and assessed for OHRQoL using the shorter version of Oral health impact profile -14 (OHIP-14) questionnaire.
Descriptive analysis of socio demographic variables and OHIP 14 was performed using Chi-square test and one way ANOVA.
Among the 90 participants, 43.3% belonged to upper lower class and 38.3% to lower class. Buccal mucosa (58.9%) was found to be the most frequent site. Among the clinical staging, Stage II (33.33%) oral cancer was more prevalent. No statistically significant differences in the OHIP mean score for Groups, I, II, III. Among the domains functional limitation was significantly different in the three groups.
Patients with oral malignancies who had been treated surgically alone had better Quality of life when compared to the combined treatment modalities.
现代肿瘤外科治疗如今关注患者治疗后的整体生活质量。需要评估现有不同治疗方式组合后的最终结果，以便做出更好的治疗决策。
本研究的目的是评估接受了各种治疗的口腔恶性肿瘤患者的口腔健康相关生活质量（OHRQoL）。
2016年10月至2017年1月期间，在印度金奈的私立医院对90名患者进行了一项横断面研究。
根据患者接受的治疗将参与者分为三组：第一组——单纯手术组；第二组——手术加放疗组；第三组——手术、化疗加放疗组，并使用口腔健康影响程度简表-14（OHIP-14）问卷评估OHRQoL。
使用卡方检验和单因素方差分析对社会人口统计学变量和OHIP 14进行描述性分析。
在90名参与者中，43.3%属于中下层阶级，38.3%属于下层阶级。颊黏膜（58.9%）是最常见的部位。在临床分期中，II期（33.33%）口腔癌最为普遍。三组的OHIP平均得分无统计学显著差异。在各个领域中，三组的功能限制存在显著差异。
与联合治疗方式相比，单纯接受手术治疗的口腔恶性肿瘤患者生活质量更好。
