酒精依赖综合征患者注意力缺陷多动障碍的家庭负担及发病风险
Family Loading and Morbidity Risk of Attention-deficit Hyperactivity Disorder in Patients with Alcohol-dependence Syndrome.
作者信息
Desai Mahesh, Bandawar Mrunal, Kandasamy Arun, Benegal Vivek
机构信息
Department of Psychiatry, KIMS, Hubli, Karnataka, India.
Department of Clinical Neurosciences, NIMHANS, Bengaluru, Karnataka, India.
出版信息
Indian J Psychol Med. 2017 Sep-Oct;39(5):659-662. doi: 10.4103/IJPSYM.IJPSYM_263_17.
BACKGROUND
Attention-deficit hyperactivity disorder (ADHD) and substance-use disorders often co-occur.
AIM
Aim of this study was to look at the family loading of ADHD (in adults and children) in patients with alcohol-dependence syndrome (ADS) along with the estimation of morbidity risk (MR) for developing ADHD.
METHODS
Thirty-five male patients with ADS along with their 369 first-degree relatives (FDRs) - both children and adults - were recruited.
RESULTS
ADHD and residual ADD (ADDRT) were significantly more common in the early-onset (EO) ADS group and their FDR. In ADHD children, high MR (27.27%) for developing EO of ADS was noted.
DISCUSSION
Findings from this study raise an avenue for research in the Indian population about the shared risk between ADS and ADHD.
背景
注意力缺陷多动障碍（ADHD）与物质使用障碍常同时出现。
目的
本研究旨在观察酒精依赖综合征（ADS）患者中ADHD（成人和儿童）的家族负荷情况，并评估患ADHD的发病风险（MR）。
方法
招募了35名患有ADS的男性患者及其369名一级亲属（FDRs），包括儿童和成人。
结果
ADHD和残留型注意力缺陷障碍（ADDRT）在早发型（EO）ADS组及其FDR中明显更为常见。在患有ADHD的儿童中，发现患早发型ADS的高发病风险（27.27%）。
讨论
本研究结果为印度人群中ADS和ADHD之间共同风险的研究开辟了一条途径。
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