Wilens Timothy E
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA.
J Clin Psychiatry. 2007;68 Suppl 11:4-8.
This report examines the developmental relationship between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUD) and associated concurrent disorders relative to adolescents and adults. ADHD is a risk factor for the development of SUD in adulthood, and it is particularly of concern with conduct and bipolar disorder comorbidities. Conversely, approximately one fifth of adults with SUD have ADHD. Individuals with SUD and ADHD have a more severe and complicated course of SUD. Pharmacotherapeutic treatment of ADHD in children reduces the risk for later cigarette smoking and SUD in adulthood.
本报告探讨了注意力缺陷多动障碍(ADHD)与物质使用障碍(SUD)之间的发展关系,以及与青少年和成年人相关的并发疾病。ADHD是成年期发生SUD的一个风险因素,尤其令人担忧的是其与品行障碍和双相情感障碍的共病情况。相反,约五分之一患有SUD的成年人患有ADHD。患有SUD和ADHD的个体,其SUD病程更为严重和复杂。对儿童ADHD进行药物治疗可降低成年后吸烟和发生SUD的风险。