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青少年起病的X连锁肾上腺脑白质营养不良表现为难治性双相情感障碍。

Adolescent-onset X-linked Adrenoleukodystrophy Presenting as Treatment-resistant Bipolar Disorder.

作者信息

Ray Anirban, Girimaji Satish Chandra, Bharath Rose Dawn

机构信息

Department of Psychiatry, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

Department of Child and Adolescent Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

出版信息

Indian J Psychol Med. 2017 Sep-Oct;39(5):685-687. doi: 10.4103/IJPSYM.IJPSYM_36_17.

DOI:10.4103/IJPSYM.IJPSYM_36_17
PMID:29200571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5688902/
Abstract

A small proportion of bipolar disorder of adolescent onset can be secondary to underlying neurological disorder (secondary mania). We report a case of treatment-resistant mania secondary to cerebral form of adrenoleukodystrophy of adolescent onset. This case demonstrates the need for clinicians to be alert to the possibility of rare neurological diseases that can present with psychiatric manifestations.

摘要

一小部分青少年期起病的双相情感障碍可能继发于潜在的神经系统疾病（继发性躁狂）。我们报告一例青少年期起病的脑型肾上腺脑白质营养不良继发的难治性躁狂病例。该病例表明临床医生有必要警惕可能以精神症状为表现的罕见神经系统疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cbf/5688902/5ba2692e2cee/IJPsyM-39-685-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cbf/5688902/5ba2692e2cee/IJPsyM-39-685-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cbf/5688902/5ba2692e2cee/IJPsyM-39-685-g001.jpg

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本文引用的文献

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J Neuropsychiatry Clin Neurosci. 2013 Summer;25(3):E20-2. doi: 10.1176/appi.neuropsych.12060142.
2
Congenital and acquired disorders presenting as psychosis in children and young adults.儿童和青年期表现为精神病的先天性和获得性疾病。
Child Adolesc Psychiatr Clin N Am. 2013 Oct;22(4):581-608. doi: 10.1016/j.chc.2013.04.004. Epub 2013 Jul 3.
3
X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management.
X 连锁肾上腺脑白质营养不良（X-ALD）：临床表现及诊断、随访和管理指南。
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Tumours of the Frontal Lobe.额叶肿瘤
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Hyperintense MRI lesions in bipolar disorder: A meta-analysis and review.双相障碍中 MRI 高信号病变：一项荟萃分析和综述。
Int Rev Psychiatry. 2009;21(4):394-409. doi: 10.1080/09540260902962198.
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An insight into the biochemistry of inborn errors of metabolism for a clinical neurologist.临床神经科医生对先天性代谢缺陷生物化学的见解。
Ann Indian Acad Neurol. 2008 Apr;11(2):68-81. doi: 10.4103/0972-2327.41873.
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