Al-Hada Naif Mohammed, Mohamed Kamari Halimah, Abdullah Che Azurahanim Che, Saion Elias, Shaari Abdul H, Talib Zainal Abidin, Matori Khamirul Amin
Department of Physics, Faculty of Science.
Materials Synthesis and Characterization Laboratory (MSCL), Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Int J Nanomedicine. 2017 Nov 20;12:8309-8323. doi: 10.2147/IJN.S150405. eCollection 2017.
In the present study, binary oxide (cadmium oxide [CdO]) (zinc oxide [ZnO]) nanoparticles (NPs) at different concentrations of precursor in calcination temperature were prepared using thermal treatment technique. Cadmium and zinc nitrates (source of cadmium and zinc) with polyvinylpyrrolidone (capping agent) have been used to prepare (CdO) (ZnO) NPs samples. The sample was characterized by X-ray diffraction (XRD), scanning electron microscopy, energy-dispersive X-ray (EDX), transmission electron microscopy (TEM), and Fourier transform infrared (FTIR) spectroscopy. XRD patterns analysis revealed that NPs were formed after calcination, which showed a cubic and hexagonal crystalline structure of (CdO) (ZnO) NPs. The phase analysis using EDX spectroscopy and FTIR spectroscopy confirmed the presence of Cd and Zn as the original compounds of prepared (CdO) (ZnO) NP samples. The average particle size of the samples increased from 14 to 33 nm as the concentration of precursor increased from x=0.20 to x=0.80, as observed by TEM results. The surface composition and valance state of the prepared product NPs were determined by X-ray photoelectron spectroscopy (XPS) analyses. Diffuse UV-visible reflectance spectra were used to determine the optical band gap through the Kubelka-Munk equation; the energy band gap was found to decrease for CdO from 2.92 to 2.82 eV and for ZnO from 3.22 to 3.11 eV with increasing x value. Additionally, photoluminescence (PL) spectra revealed that the intensity in PL increased with an increase in particle size. In addition, the antibacterial activity of binary oxide NP was carried out in vitro against ATCC 25922 Gram (-ve), ATCC 10708, and UPMC 1175 Gram (+ve). This study indicated that the zone of inhibition of 21 mm has good antibacterial activity toward the Gram-positive UPMC 1175.
在本研究中，采用热处理技术制备了在不同煅烧温度下具有不同前驱体浓度的二元氧化物（氧化镉[CdO]）（氧化锌[ZnO]）纳米颗粒（NPs）。硝酸镉和硝酸锌（镉和锌的来源）与聚乙烯吡咯烷酮（封端剂）被用于制备（CdO）（ZnO）NPs样品。通过X射线衍射（XRD）、扫描电子显微镜、能量色散X射线（EDX）、透射电子显微镜（TEM）和傅里叶变换红外（FTIR）光谱对样品进行了表征。XRD图谱分析表明，煅烧后形成了NPs，其显示出（CdO）（ZnO）NPs的立方和六方晶体结构。使用EDX光谱和FTIR光谱进行的相分析证实了Cd和Zn作为制备的（CdO）（ZnO）NP样品的原始化合物的存在。如TEM结果所示，随着前驱体浓度从x = 0.20增加到x = 0.80，样品的平均粒径从14 nm增加到33 nm。通过X射线光电子能谱（XPS）分析确定了制备的产物NPs的表面组成和价态。利用漫反射紫外可见光谱通过Kubelka-Munk方程确定光学带隙；随着x值的增加，发现CdO的能带隙从2.92 eV降低到2.82 eV，ZnO的能带隙从3.22 eV降低到3.11 eV。此外发光（PL）光谱表明，PL强度随着粒径的增加而增加。此外，对二元氧化物NP的抗菌活性进行了体外测试，针对的是ATCC 25922革兰氏阴性菌、ATCC 10708和UPMC 1175革兰氏阳性菌。本研究表明，21 mm的抑菌圈对革兰氏阳性菌UPMC 1175具有良好的抗菌活性。
