Coattrenec Y, Jaques D, Jandus P, Harr T, Spoerl D
Division of Immunology and Allergology, Department of Medical Specialties, University Hospital and Medical Faculty, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva, Switzerland.
Dr. med. Dominique Jaques, Rue Emile-Yung 11, 1205 Geneva, Switzerland.
Allergy Asthma Clin Immunol. 2017 Nov 24;13:50. doi: 10.1186/s13223-017-0221-x. eCollection 2017.
The castor bean plant, , is known to have allergenic and toxic properties. Castor bean allergy has been described mainly as an occupational inhalation allergy in laboratory workers, in persons working in oil processing mills or in agricultural industry. So far, only one case of anaphylactic reaction due to castor bean sensitization confirmed by specific IgE has been described in literature.
A 30-year-old woman presented to the emergency room with severe angioedema followed by urticaria, hypotension and tachycardia. She recovered after treatment with antihistamines, corticosteroids, nebulized adrenaline and intravenous fluids. Food induced anaphylaxis was excluded by allergological investigations. After repeated thorough history, the patient mentioned having bitten into a castor bean just before the reaction. Cutaneous test (prick-to-prick) and specific IgE for castor bean were highly positive.
We report the second case of a severe anaphylactic reaction to castor beans, confirmed by IgE testing, reported in the literature. It underlines the importance of a meticulous history in allergology and highlights the fact, that castor beans may cause potentially fatal anaphylaxis.
蓖麻植株已知具有致敏和毒性特性。蓖麻过敏主要被描述为实验室工作人员、从事油加工厂工作或农业行业人员的职业性吸入过敏。迄今为止,文献中仅描述了一例经特异性IgE证实的因蓖麻致敏导致的过敏反应病例。
一名30岁女性因严重血管性水肿就诊于急诊室,随后出现荨麻疹、低血压和心动过速。经使用抗组胺药、皮质类固醇、雾化肾上腺素和静脉输液治疗后康复。过敏学检查排除了食物诱发的过敏反应。经过反复详细询问病史,患者提到在反应发生前刚咬了一颗蓖麻籽。皮肤试验(点刺试验)和蓖麻籽特异性IgE检测均呈强阳性。
我们报告了文献中第二例经IgE检测证实的对蓖麻籽严重过敏反应的病例。这强调了在过敏学中详细询问病史的重要性,并突出了蓖麻籽可能导致潜在致命过敏反应这一事实。