Wedin G P, Neal J S, Everson G W, Krenzelok E P
Am J Emerg Med. 1986 May;4(3):259-61. doi: 10.1016/0735-6757(86)90080-x.
Although the highly toxic nature of castor bean (Ricinus communis) is well recognized, reports of human toxicity in the English medical literature are scarce. The potentially lethal doses reported for children and adults are three beans and four to eight beans respectively. Recent experience with two cases provides added insight into the expected course of toxicity. In both cases, repeated vomiting, diarrhea, and transiently elevated serum creatinine occurred. Dehydration was much more pronounced in the second case. Both patients recovered uneventfully. Other reported manifestations of castor bean toxicity, such as hepatic necrosis, renal failure, erythrocyte hemolysis, convulsions, and shock, did not occur.
尽管蓖麻子(Ricinus communis)的高毒性已广为人知,但英文医学文献中关于人类中毒的报道却很少。据报道,儿童和成人的潜在致死剂量分别为三颗蓖麻子和四至八颗蓖麻子。最近两例病例的经验为毒性的预期病程提供了更多见解。在这两例病例中,均出现了反复呕吐、腹泻以及血清肌酐短暂升高的情况。第二例病例中的脱水更为明显。两名患者均顺利康复。蓖麻子毒性的其他报道表现,如肝坏死、肾衰竭、红细胞溶血、惊厥和休克,均未出现。