Moghadamnia Yasaman, Moslemi Dariush
Alzahra University, Tehran, Iran.
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Caspian J Intern Med. 2017 Fall;8(4):258-263. doi: 10.22088/cjim.8.4.258.
Due to the rate increase in cancer incidence, many researchers in different fields have been conducting studies on cancer-related phenomena. Most studies are conducted to focus on cellular and molecular aspects of cancerous diseases and treatment strategies. Physicists have been using mathematical modeling and simulation to explain the growth pattern of tumors. Although most published studies in this area still have not gained the needed maturity for "treating cancer", research has helped with the statistical laws of growth, predation and proliferation of cancer cells. In this review, a brief explanation of mathematical models for tumor growth is presented, followed by a discussion on treatment simulations, introducing white noise as one of the clinical remedies in the original model.
由于癌症发病率的上升,不同领域的许多研究人员一直在对癌症相关现象进行研究。大多数研究聚焦于癌症疾病的细胞和分子层面以及治疗策略。物理学家一直在使用数学建模和模拟来解释肿瘤的生长模式。尽管该领域大多数已发表的研究在“治疗癌症”方面仍未达到所需的成熟度,但研究有助于了解癌细胞生长、捕食和增殖的统计规律。在本综述中,首先简要解释了肿瘤生长的数学模型,随后讨论了治疗模拟,并引入白噪声作为原始模型中的临床治疗方法之一。