Shirvani Mahshid, Vakili Sadeghi Mohsen, Hosseini Seyed Reza, Bijani Ali, Ghadimi Reza
Student Research Committee, Babol University of Medical Sciences, Babol. Iran.
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Caspian J Intern Med. 2017 Fall;8(4):305-310. doi: 10.22088/cjim.8.4.305.
There is some evidence that shows the symptoms of anemia are fewere in overweight and obese people, so, the purpose of this research was to study the relationship between anemia and iron deficiency anemia (IDA) with lipid profile status of the elderly.
This cross-sectional study came from the Amirkola Health and Ageing Project (AHAP). A demographic questionnaire was given to the older people and a blood sample was obtained to assay their lipid indexes (triglyceride, cholesterol, HDL and LDL) and the parameters related to anemia after 12 hours fasting. The data were analyzed by chi-square test, t-test and Pearson correlation using SPSS. A p<0.05 was considered as the significance level of the tests.
The average age of the people was 68.95±7.43 years old. In this study, the prevalence of anemia and IDA was 31% and 9%, respectively. The mean concentration of serum triglyceride, cholesterol and LDL in the anemia group and the IDA group was less than the control groups. The amount of HDL in different groups was almost the same, although the difference was statistically significant with respect to variables like age and obesity (P=0.001).
The study showed that the amount of lipid profile (triglyceride and cholesterol) in the elderly with anemia and IDA was less compared to other people. This result was achieved in some other research studies too, but further research is suggested to find possible mechanisms.
有证据表明超重和肥胖人群的贫血症状较少,因此,本研究的目的是探讨老年人贫血及缺铁性贫血(IDA)与血脂状况之间的关系。
这项横断面研究来自阿米科拉健康与老龄化项目(AHAP)。向老年人发放人口统计学调查问卷,并在禁食12小时后采集血样,以检测他们的血脂指标(甘油三酯、胆固醇、高密度脂蛋白和低密度脂蛋白)以及与贫血相关的参数。使用SPSS软件通过卡方检验、t检验和Pearson相关性分析数据。p<0.05被视为检验的显著性水平。
研究对象的平均年龄为68.95±7.43岁。在本研究中,贫血和IDA的患病率分别为31%和9%。贫血组和IDA组的血清甘油三酯、胆固醇和低密度脂蛋白的平均浓度低于对照组。不同组的高密度脂蛋白水平几乎相同,尽管在年龄和肥胖等变量方面差异具有统计学意义(P=0.001)。
研究表明,与其他人相比,患有贫血和IDA的老年人的血脂水平(甘油三酯和胆固醇)较低。其他一些研究也得出了这一结果,但建议进一步研究以找出可能的机制。