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同步性多发性神经内分泌肺肿瘤的外科治疗(病例系列):越多就越好吗?

Surgical treatment of synchronous multiple neuroendocrine lung tumours (case series): is more always better?

作者信息

Brandolini Jury, Bertolaccini Luca, Pardolesi Alessandro, Solli Piergiorgio

机构信息

Department of Thoracic Surgery, AUSL Romagna Teaching Hospitals, Forlì, Italy.

出版信息

Ann Transl Med. 2017 Nov;5(21):423. doi: 10.21037/atm.2017.08.13.

Abstract

Pulmonary neuroendocrine lung tumours are uncommon neoplasm; the presence of multiple and synchronous lesions is rare, and few case report are described in the literature. We present a case series of three patients without particular symptom and radiologic finding of multiple synchronous pulmonary nodules. All the patients underwent surgical treatment; histopathologic examination revealed typical carcinoid tumours in all three cases (one patient has a synchronous atypical carcinoid). No oncological progressions were observed at follow-up. A review of current literature is also presented with a suggested strategy management.

摘要

肺神经内分泌肿瘤是一种罕见的肿瘤;出现多个同步病灶的情况很少见,文献中描述的病例报告也很少。我们报告了一组三例患者的病例系列,这些患者没有特殊症状,影像学检查发现多个同步肺结节。所有患者均接受了手术治疗;组织病理学检查显示三例均为典型类癌肿瘤(其中一例患者同时患有非典型类癌)。随访期间未观察到肿瘤进展。本文还对当前文献进行了综述,并提出了建议的治疗策略。

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