Kashani Parvin, Safari Saeed, Hatamabadi Hamidreza, Arhami Dolatabadi Ali, Manouchehrifar Mohammad, Dokht Tabrizi Maryam
Emergency Department, Loghmane Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Emergency Department, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Emerg (Tehran). 2017;5(1):e80. doi: 10.22037/emergency.v5i1.18780. Epub 2017 Oct 13.
Each year a large number of patients present to emergency departments (EDs) following accidental or intentional poisoning with methadone. This study was designed with the aim of demographic evaluation of methadone poisoning in children presenting to ED and proposing preventive measures to parents and the healthcare system.
This cross sectional study was carried out on children under the age of 12 years presenting to ED of a poisoning referral center. Demographic characteristics of the child and parents, cause of poisoning, form of drug consumed, dose consumed, the symptoms of the child on admission, clinical examination, laboratory findings, and final outcome were recorded and reported using descriptive statistics.
179 cases were studied (59.2% boys). Cause of consumption was accidental in 175 (97.8%) cases and consumed drug dose was unknown in 53 (53.6%) cases. On admission 6 cases were in deep coma, 133 (74.3%) had miotic pupils, and 52 (29.1%) were affected with respiratory apnea and cyanosis. In 132 (73.8%) cases drugs were obtained from unapproved stores and form of drug consumed was syrup in 146 (81.6%) cases. 177 (98.9%) cases were discharged after 2 or3 days and 2 (1.1%) cases died.
Based on the results of the present study, most cases of methadone poisoning were accidental, in children residing in poor and middle-class areas, with parents who had a low level of education and had obtained the drug from unapproved stores and stored it in improper containers or at improper places. Only 64.8% of the parents were educated regarding drug storage.
每年都有大量患者在意外或故意服用美沙酮中毒后前往急诊科就诊。本研究旨在对前往急诊科就诊的儿童美沙酮中毒情况进行人口统计学评估,并向家长和医疗系统提出预防措施。
本横断面研究针对前往中毒转诊中心急诊科就诊的12岁以下儿童开展。记录并使用描述性统计方法报告儿童及其父母的人口统计学特征、中毒原因、所服用药物的剂型、服用剂量、入院时儿童的症状、临床检查、实验室检查结果以及最终结局。
共研究了179例病例(男孩占59.2%)。175例(97.8%)的中毒原因是意外,53例(53.6%)所服用药物的剂量未知。入院时,6例处于深度昏迷,133例(74.3%)瞳孔缩小,52例(29.1%)出现呼吸暂停和发绀。132例(73.8%)的药物来自未经批准的商店,146例(81.6%)所服用药物的剂型为糖浆。177例(98.9%)在2或3天后出院,2例(1.1%)死亡。
根据本研究结果,大多数美沙酮中毒病例是意外发生的,中毒儿童居住在中低收入地区,其父母教育程度较低,从未经批准的商店获取药物并将其储存在不当容器或不当位置。只有64.8%的家长接受过关于药物储存的教育。