• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Characteristics of Methadone Intoxicated Children Presenting to Emergency Department; a Cross Sectional Study.急诊科收治的美沙酮中毒儿童的特征;一项横断面研究。
Emerg (Tehran). 2017;5(1):e80. doi: 10.22037/emergency.v5i1.18780. Epub 2017 Oct 13.
2
Clinical Signs and Symptoms and Laboratory Findings of Methadone Poisoning in Children.儿童美沙酮中毒的临床体征、症状及实验室检查结果
Iran J Pediatr. 2015 Feb;25(1):e176. doi: 10.5812/ijp.176. Epub 2015 Jan 17.
3
Methadone toxicity: comparing tablet and syrup formulations during a decade in an academic poison center of Iran.美沙酮中毒:伊朗一学术毒理中心十年来比较片剂和糖浆制剂。
Clin Toxicol (Phila). 2013 Sep-Oct;51(8):777-82. doi: 10.3109/15563650.2013.830732. Epub 2013 Aug 23.
4
An Epidemiologic Study of Pediatric Poisoning; a Six-month Cross-sectional Study.一项小儿中毒的流行病学研究;一项为期六个月的横断面研究。
Emerg (Tehran). 2016 Winter;4(1):21-4.
5
Predictive Factors of Treatment Outcomes for Hospital Care in Children with Acute Methadone Poisoning.急性美沙酮中毒儿童住院治疗结局的预测因素
J Res Pharm Pract. 2018 Oct-Dec;7(4):200-204. doi: 10.4103/jrpp.JRPP_16_141.
6
Predisposing Factors for Methadone Poisoning in Children Hospitalized at Kerman Afzalipour Hospital, Iran.伊朗克尔曼阿夫扎利普尔医院收治的儿童美沙酮中毒的诱发因素
Addict Health. 2016 Winter;8(1):61-6.
7
Accidental children poisoning with methadone: an Iranian pediatric sectional study.儿童意外美沙酮中毒:一项伊朗儿科横断面研究。
Iran J Child Neurol. 2013 Fall;7(4):32-4.
8
Poisoning in children and adolescents in Kermanshah city, Iran.伊朗克尔曼沙阿市儿童和青少年中毒情况。
BMC Pediatr. 2024 Feb 22;24(1):135. doi: 10.1186/s12887-024-04631-3.
9
Methadone toxicity in a poisoning referral center.一家中毒转诊中心的美沙酮中毒情况
J Res Pharm Pract. 2013 Jul;2(3):130-4. doi: 10.4103/2279-042X.122387.
10
Pattern of acute poisonings in childhood in Ankara: what has changed in twenty years?安卡拉儿童急性中毒模式:二十年来有何变化?
Turk J Pediatr. 2004 Apr-Jun;46(2):147-52.

引用本文的文献

1
Delayed hypoxic encephalopathy: a rare complication of methadone poisoning in two cases.迟发性缺氧性脑病:两例美沙酮中毒的罕见并发症
Iran J Child Neurol. 2022 Summer;16(3):213-217. doi: 10.22037/ijcn.v16i2.27372. Epub 2022 Jul 16.
2
Stress Cardiomyopathy (Takotsubo syndrome) Following Accidental Methadone Poisoning; Report of Two Pediatric Cases.意外美沙酮中毒后发生的应激性心肌病( Takotsubo综合征);两例儿科病例报告
Arch Acad Emerg Med. 2019 Mar 9;7(1):e22. eCollection 2019.

本文引用的文献

1
Clinical Signs and Symptoms and Laboratory Findings of Methadone Poisoning in Children.儿童美沙酮中毒的临床体征、症状及实验室检查结果
Iran J Pediatr. 2015 Feb;25(1):e176. doi: 10.5812/ijp.176. Epub 2015 Jan 17.
2
Accidental children poisoning with methadone: an Iranian pediatric sectional study.儿童意外美沙酮中毒:一项伊朗儿科横断面研究。
Iran J Child Neurol. 2013 Fall;7(4):32-4.
3
Effectiveness of naltrexone in the prevention of delayed respiratory arrest in opioid-naive methadone-intoxicated patients.纳曲酮预防阿片类药物初治的美沙酮中毒患者呼吸抑制延迟的效果。
Biomed Res Int. 2013;2013:903172. doi: 10.1155/2013/903172. Epub 2013 Sep 9.
4
Methadone toxicity: comparing tablet and syrup formulations during a decade in an academic poison center of Iran.美沙酮中毒:伊朗一学术毒理中心十年来比较片剂和糖浆制剂。
Clin Toxicol (Phila). 2013 Sep-Oct;51(8):777-82. doi: 10.3109/15563650.2013.830732. Epub 2013 Aug 23.
5
Accidental and non-accidental ingestion of methadone and buprenorphine in childhood: a single center experience, 1999-2009.儿童意外和非意外摄入美沙酮及丁丙诺啡:单中心经验(1999 - 2009年)
Curr Drug Saf. 2011 Feb 1;6(1):12-6. doi: 10.2174/157488611794480034.
6
Hallmarks of opium poisoning in infants and toddlers.婴幼儿鸦片中毒的特征。
Trop Doct. 2010 Oct;40(4):220-2. doi: 10.1258/td.2010.100134. Epub 2010 Aug 31.
7
Accidental methadone poisoning in children: a call for Canadian research action.儿童意外美沙酮中毒:呼吁加拿大开展研究行动。
Child Abuse Negl. 2010 Aug;34(8):553-4. doi: 10.1016/j.chiabu.2010.02.002. Epub 2010 Jun 2.
8
Prevalence of long QTc interval in methadone maintenance patients.美沙酮维持治疗患者中长QTc间期的患病率。
Drug Alcohol Depend. 2009 Jan 1;99(1-3):327-32. doi: 10.1016/j.drugalcdep.2008.06.018. Epub 2008 Sep 5.
9
Onset of symptoms after methadone overdose.美沙酮过量后的症状发作。
Am J Emerg Med. 2007 Jan;25(1):57-9. doi: 10.1016/j.ajem.2006.07.006.
10
Fatal methadone poisoning in children: Maryland 1992-1996.儿童致命性美沙酮中毒:1992 - 1996年的马里兰州
Subst Use Misuse. 2000 Aug;35(9):1141-8. doi: 10.3109/10826080009147476.

急诊科收治的美沙酮中毒儿童的特征;一项横断面研究。

Characteristics of Methadone Intoxicated Children Presenting to Emergency Department; a Cross Sectional Study.

作者信息

Kashani Parvin, Safari Saeed, Hatamabadi Hamidreza, Arhami Dolatabadi Ali, Manouchehrifar Mohammad, Dokht Tabrizi Maryam

机构信息

Emergency Department, Loghmane Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Emergency Department, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Emerg (Tehran). 2017;5(1):e80. doi: 10.22037/emergency.v5i1.18780. Epub 2017 Oct 13.

DOI:10.22037/emergency.v5i1.18780
PMID:29201962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5703757/
Abstract

INTRODUCTION

Each year a large number of patients present to emergency departments (EDs) following accidental or intentional poisoning with methadone. This study was designed with the aim of demographic evaluation of methadone poisoning in children presenting to ED and proposing preventive measures to parents and the healthcare system.

METHODS

This cross sectional study was carried out on children under the age of 12 years presenting to ED of a poisoning referral center. Demographic characteristics of the child and parents, cause of poisoning, form of drug consumed, dose consumed, the symptoms of the child on admission, clinical examination, laboratory findings, and final outcome were recorded and reported using descriptive statistics.

RESULTS

179 cases were studied (59.2% boys). Cause of consumption was accidental in 175 (97.8%) cases and consumed drug dose was unknown in 53 (53.6%) cases. On admission 6 cases were in deep coma, 133 (74.3%) had miotic pupils, and 52 (29.1%) were affected with respiratory apnea and cyanosis. In 132 (73.8%) cases drugs were obtained from unapproved stores and form of drug consumed was syrup in 146 (81.6%) cases. 177 (98.9%) cases were discharged after 2 or3 days and 2 (1.1%) cases died.

CONCLUSION

Based on the results of the present study, most cases of methadone poisoning were accidental, in children residing in poor and middle-class areas, with parents who had a low level of education and had obtained the drug from unapproved stores and stored it in improper containers or at improper places. Only 64.8% of the parents were educated regarding drug storage.

摘要

引言

每年都有大量患者在意外或故意服用美沙酮中毒后前往急诊科就诊。本研究旨在对前往急诊科就诊的儿童美沙酮中毒情况进行人口统计学评估,并向家长和医疗系统提出预防措施。

方法

本横断面研究针对前往中毒转诊中心急诊科就诊的12岁以下儿童开展。记录并使用描述性统计方法报告儿童及其父母的人口统计学特征、中毒原因、所服用药物的剂型、服用剂量、入院时儿童的症状、临床检查、实验室检查结果以及最终结局。

结果

共研究了179例病例(男孩占59.2%)。175例(97.8%)的中毒原因是意外,53例(53.6%)所服用药物的剂量未知。入院时,6例处于深度昏迷,133例(74.3%)瞳孔缩小,52例(29.1%)出现呼吸暂停和发绀。132例(73.8%)的药物来自未经批准的商店,146例(81.6%)所服用药物的剂型为糖浆。177例(98.9%)在2或3天后出院,2例(1.1%)死亡。

结论

根据本研究结果,大多数美沙酮中毒病例是意外发生的,中毒儿童居住在中低收入地区,其父母教育程度较低,从未经批准的商店获取药物并将其储存在不当容器或不当位置。只有64.8%的家长接受过关于药物储存的教育。