Fradet G, Evans K G, Nelems B, Miller R R, Müller N L
Department of Surgery, Vancouver General Hospital, University of British Columbia, BC.
Can J Surg. 1989 Mar;32(2):139-42.
A review of 33 months' experience with primary anterior mediastinal masses in 31 patients disclosed that in 9 (29%) the tumour was benign. Nineteen (86%) of the 22 malignant tumours and only 2 of the 9 benign tumours were symptomatic. Diagnosis was established by histopathologic examination of a biopsy specimen or resected tissue and serum radioimmunoassay for alpha-fetoprotein or human chorionic gonadotropin, beta-subunit. The authors present an investigational algorithm, using modern procedures, to facilitate the diagnosis of this relatively uncommon and challenging condition.
对31例原发性前纵隔肿块患者33个月的经验回顾显示，9例（29%）肿瘤为良性。22例恶性肿瘤中有19例（86%）有症状，而9例良性肿瘤中只有2例有症状。通过活检标本或切除组织的组织病理学检查以及血清甲胎蛋白或人绒毛膜促性腺激素β亚单位的放射免疫测定来确诊。作者提出了一种使用现代方法的研究性算法，以促进对这种相对罕见且具有挑战性的病症的诊断。
