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探讨体外膜肺氧合在疑似或确诊自杀未遂患者中的作用:一项病例系列研究。

Examining the role of extracorporeal membrane oxygenation in patients following suspected or confirmed suicide attempts: A case series.

机构信息

Department of Medicine, Alpert Medical School of Brown University, Providence, RI, United States.

Lifespan Hospital System, Providence, RI, United States.

出版信息

J Crit Care. 2018 Apr;44:445-449. doi: 10.1016/j.jcrc.2017.10.025. Epub 2017 Oct 18.

Abstract

The decision to offer extracorporeal membrane oxygenation (ECMO) is based on a risk/benefit assessment and the likelihood of a treatable underlying condition or the feasibility of destination therapy (durable mechanical support or thoracic organ transplantation) should heart-lung function fail to improve. Patients who present following suspected suicide attempts who fail medical therapy may pose a dilemma for clinicians. An assessment to determine if a patient has a high likelihood of psychiatric recovery such that bridging with ECMO or ultimately destination therapy could or should be offered is not always feasible in the setting of critical illness. This case series reviews our institution's experience with ECMO in the management of five patients who presented following suspected or confirmed suicide attempts. All five patients survived to hospital discharge. Two had subsequent psychiatric admissions, one following a repeat suicide attempt. A discussion of these cases demonstrates the effectiveness of ECMO in supporting this group of patients in the short-term. The self-limited natural history of many psychiatric episodes, poisonings and traumatic injuries makes the use of ECMO a potentially reasonable support strategy. However, careful consideration must be given to psychiatric history and follow-up given the substantial commitment of resources, potential for complications and for stranding patients on extracorporeal therapy without definitive destination therapy.

摘要

提供体外膜肺氧合(ECMO)的决定基于风险/效益评估,以及在心肺功能未能改善的情况下,潜在可治疗的基础疾病或可行的终末治疗(持久机械支持或胸部器官移植)的可能性。在心肺复苏治疗失败后出现的疑似自杀未遂的患者可能会给临床医生带来困境。在重症疾病的情况下,评估患者是否有很高的精神康复可能性,以便通过 ECMO 或最终的终末治疗进行桥接,这种评估并不总是可行的。本病例系列回顾了我们机构在管理五名疑似或确诊自杀未遂后接受 ECMO 治疗的患者方面的经验。所有五名患者均存活至出院。其中两名随后被收治精神病院,一名在重复自杀未遂后被收治。这些病例的讨论表明 ECMO 在支持这群患者的短期治疗中是有效的。许多精神发作、中毒和创伤性损伤的自限性自然病史使得 ECMO 的使用成为一种潜在合理的支持策略。然而,必须考虑到精神病史和随访,因为这需要大量的资源投入,可能会出现并发症,并且如果没有明确的终末治疗,患者可能会被困在体外治疗上。

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