Petermann Fanny, Díaz-Martínez Ximena, Garrido-Méndez Álex, Leiva Ana María, Martínez María Adela, Salas Carlos, Poblete-Valderrama Felipe, Celis-Morales Carlos
BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, United Kingdom.
Grupo de Investigación Calidad de Vida, Departamento de Ciencias de la Educación, Universidad del Biobío, Chillán, Chile.
Gac Sanit. 2018 May-Jun;32(3):230-235. doi: 10.1016/j.gaceta.2017.09.008. Epub 2017 Dec 6.
To investigate whether the association between type 2 diabetes (T2D) and family history of diabetes is modified by the levels of physical activity in the Chilean population.
In this study were included 5129 participants from the cross-sectional 2009-2010 National Health Survey. Physical activity level was assessed using the Global Physical Activity Questionnaire and family history of T2D, through self-reporting. The association between diabetes, family history of diabetes and physical activity was determined using logistic regression.
The odds of developing T2D in people with family history of this pathology is high, independent of their levels of physical activity and adiposity. Both men and women with family history of T2D have a higher probability of developing T2D. The odds ratio for having T2D was 5,49 (95%CI: 3,85-7,84; p <0,0001) in women, and 8,16 (95%CI: 4,96-13,4; p <0,0001) in men with family history of T2D and low levels of physical activity in comparison to those with high levels of physical activity and without a family history.
Given the elevated risk of developing T2D presented by individuals with a family history of this pathology, and the effect of physical activity in reducing such risk, people with family history of diabetes may need higher levels of physical activity to attenuate their susceptibility to T2D.
研究智利人群中2型糖尿病(T2D)与糖尿病家族史之间的关联是否会因身体活动水平而改变。
本研究纳入了2009 - 2010年全国健康横断面调查的5129名参与者。使用全球身体活动问卷评估身体活动水平,并通过自我报告获取T2D家族史。使用逻辑回归确定糖尿病、糖尿病家族史与身体活动之间的关联。
有这种疾病家族史的人患T2D的几率很高,与他们的身体活动水平和肥胖程度无关。有T2D家族史的男性和女性患T2D的可能性都更高。与身体活动水平高且无家族史的人相比,有T2D家族史且身体活动水平低的女性患T2D的比值比为5.49(95%CI:3.85 - 7.84;p <0.0001),男性为8.16(95%CI:4.96 - 13.4;p <0.0001)。
鉴于有这种疾病家族史的个体患T2D的风险升高,以及身体活动在降低此类风险方面的作用,有糖尿病家族史的人可能需要更高水平的身体活动来减弱他们患T2D的易感性。