Awaad Amani S, Alothman Monerah R, Zain Yara M, Zain Ghada M, Alqasoumi Saleh I, Hassan Dina A
Pharmacognosy Department, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Botany and Microbiology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Saudi Pharm J. 2017 Dec;25(8):1226-1230. doi: 10.1016/j.jsps.2017.09.007. Epub 2017 Sep 20.
Plants are excellent sources of nutrition and highly bioactive substances that might use in the development of new drugs and pharmaceutical agents. Three species of the Genus (Family Euphorpiaceae), namely; Forssk, L., Linn growing in Ryiadh, KSA were air-dried, powdered, and their active materials were extracted with alcohol. The nutritional value phytochemical constituents and antimicrobial activity of the plants were determined. The chemical contents were similar in the three species; however, lipid profile of the plants showed that the stearic acid and lignoceric acid were detected only in and while palmitoleic acid was detected only in . The percentage of unsaturated fatty acid methyl esters were 52.48%, 69.39% and 66.52% in , , , respectively. Three compounds, 1-ethoxypentacosane, heptacosan-1-ol and β-sitosterol were isolated from the three plant extracts and identified using different spectroscopic analysis. The percentage of crude protein was 43.65%, 25.00% and 18.75% in , and , respectively. The free amino acids and amino acid composition were quantitatively determined using amino acid analyzer. All the plant extracts were active against bacterial and fungal test organisms, however, the antimicrobial activity were varied according to both the species and the test organism.
植物是营养和高生物活性物质的优质来源，这些物质可用于新药和药剂的开发。大戟科（Euphorbiaceae）某属的三个物种，即生长在沙特阿拉伯利雅得的Forssk、L.、Linn，经过风干、研磨成粉，并用酒精提取其活性物质。测定了这些植物的营养价值、植物化学成分和抗菌活性。这三个物种的化学含量相似；然而，这些植物的脂质谱显示，硬脂酸和木蜡酸仅在[物种名称1]和[物种名称2]中检测到，而棕榈油酸仅在[物种名称3]中检测到。[物种名称1]、[物种名称2]、[物种名称3]中不饱和脂肪酸甲酯的百分比分别为52.48%、69.39%和66.52%。从这三种植物提取物中分离出三种化合物，1-乙氧基二十五烷、二十七烷-1-醇和β-谷甾醇，并通过不同的光谱分析进行鉴定。[物种名称1]、[物种名称2]和[物种名称3]中粗蛋白的百分比分别为43.65%、25.00%和18.75%。使用氨基酸分析仪对游离氨基酸和氨基酸组成进行了定量测定。所有植物提取物对细菌和真菌测试菌株均有活性，然而，抗菌活性因物种和测试菌株而异。
