Faculty of Health, University of Tasmania, Hobart, Australia.
Faculty of Health, Federation University, Ballarat, Australia.
Curr Pharm Des. 2018;24(9):999-1006. doi: 10.2174/1381612824666171204151209.
Studies indicate that Polycystic Ovarian Syndrome (PCOS) features (e.g. insulin instability, food cravings, overproduction of androgens and menstrual irregularities) are associated with increased appetite, impaired impulse control and feelings of body dissatisfaction. Counter intuitively, binge eating behaviors have been shown to reinforce PCOS symptomatology, precipitating concurrently body dissatisfaction, weight gain, insulin instability and overproduction of androgens. The present systematic literature review aspires to investigate the relationship between binge eating, in the broader context of eating disorder behaviors, and Polycystic Ovarian Syndrome (PCOS), taking into account shared characteristics between EDs (Eating Disorders) and PCOS. To address this aim, the PRISMA guidelines are adopted. A total of 21 studies, which investigated the presence of binge eating in PCOS population and the presence of PCOS in EDs population, were synthesized. Findings suggested that an increased prevalence of binge eating has been reported in women with Polycystic Ovarian Syndrome (PCOS); and that women suffering from BN (Bulimia Nervosa) and BED (Binge Eating Disorder) are more likely to display polycystic ovaries. Further research on their shared liability is required in order to inform more efficient prevention and treatment initiatives for populations presenting with comorbid features.
研究表明多囊卵巢综合征（PCOS）的特征（如胰岛素不稳定、食欲旺盛、雄激素过多和月经不规律）与食欲增加、冲动控制受损和身体不满有关。反直觉的是，暴食行为被证明会加重 PCOS 的症状，同时导致身体不满、体重增加、胰岛素不稳定和雄激素过多。本系统文献综述旨在探讨在更广泛的饮食障碍行为背景下，暴食行为与多囊卵巢综合征（PCOS）之间的关系，并考虑到 ED（饮食障碍）和 PCOS 之间的共同特征。为此，采用 PRISMA 指南。共综合了 21 项研究，这些研究调查了 PCOS 人群中暴食行为的存在以及 ED 人群中 PCOS 的存在。研究结果表明，多囊卵巢综合征（PCOS）女性暴食行为的发生率增加；患有 BN（神经性贪食症）和 BED（暴食障碍）的女性更有可能表现出多囊卵巢。需要进一步研究它们的共同易感性，以便为具有共病特征的人群提供更有效的预防和治疗措施。
