马来西亚半岛农民工中淋巴丝虫病的血清流行率。
Seroprevalence of lymphatic filariasis among migrant workers in Peninsular Malaysia.
作者信息
Noordin Rahmah, Mohd Zain Siti Nursheena, Yunus Muhammad Hafiznur, Sahimin Norhidayu
机构信息
Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang.
Institute of Biological Science, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
出版信息
Trans R Soc Trop Med Hyg. 2017 Aug 1;111(8):370-372. doi: 10.1093/trstmh/trx062.
BACKGROUND
Malaysia aims to eliminate lymphatic filariasis (LF) by the year 2020, thus the potential threat of LF from migrant workers needs to be investigated.
METHODS
Brugian and bancroftian filariasis among 484 migrant workers from six countries were investigated using rapid tests based on detection of specific IgG4 antibodies against BmR1 (Brugia Rapid) and BmSXP recombinant antigens.
RESULTS
The seroprevalence of brugian filariasis was very low; however, bancroftian filariasis was notable among workers from India, Nepal and Myanmar.
CONCLUSION
Malaysia is not endemic for Wuchereria bancrofti, but harbors the vectors for the parasite, thus the results showed that migrant workers should be monitored for this infection.
背景
马来西亚的目标是到2020年消除淋巴丝虫病（LF），因此需要调查外来务工人员带来的LF潜在威胁。
方法
采用基于检测针对BmR1（布鲁吉亚快速检测）和BmSXP重组抗原的特异性IgG4抗体的快速检测方法，对来自六个国家的484名外来务工人员中的布鲁吉亚丝虫病和班氏丝虫病进行调查。
结果
布鲁吉亚丝虫病的血清阳性率非常低；然而，班氏丝虫病在来自印度、尼泊尔和缅甸的务工人员中较为显著。
结论
马来西亚并非班氏吴策线虫的流行地区，但存在该寄生虫的传播媒介，因此结果表明应对外来务工人员进行这种感染的监测。
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