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CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation - A target for novel cancer therapy.
Cancer Treat Rev. 2018 Feb;63:40-47. doi: 10.1016/j.ctrv.2017.11.007. Epub 2017 Nov 26.
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CXCR3 Ligands in Cancer and Autoimmunity, Chemoattraction of Effector T Cells, and Beyond.
Front Immunol. 2020 May 29;11:976. doi: 10.3389/fimmu.2020.00976. eCollection 2020.
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Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity--a tale of conflict and conundrum.
Neuropathol Appl Neurobiol. 2010 Aug;36(5):368-87. doi: 10.1111/j.1365-2990.2010.01089.x. Epub 2010 May 6.
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Interferons induce CXCR3-cognate chemokine production by human metastatic melanoma.
J Immunother. 2010 Nov-Dec;33(9):965-74. doi: 10.1097/CJI.0b013e3181fb045d.
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Expression and regulation of the CXCL9-11 chemokines and CXCR3 receptor in Atlantic salmon .
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Regulation of CXCL9/10/11 in oral keratinocytes and fibroblasts.
J Dent Res. 2008 Dec;87(12):1160-5. doi: 10.1177/154405910808701211.
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Targeting CXCL9/10/11-CXCR3 axis: an important component of tumor-promoting and antitumor immunity.
Clin Transl Oncol. 2023 Aug;25(8):2306-2320. doi: 10.1007/s12094-023-03126-4. Epub 2023 Apr 19.
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Interleukin-27 and IFNγ regulate the expression of CXCL9, CXCL10, and CXCL11 in hepatitis.
J Mol Med (Berl). 2015 Dec;93(12):1355-67. doi: 10.1007/s00109-015-1319-6. Epub 2015 Jul 23.
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Dual specificity of anti-CXCL10-CXCL9 antibodies is governed by structural mimicry.
J Biol Chem. 2012 Jan 6;287(2):1458-67. doi: 10.1074/jbc.M111.253658. Epub 2011 Oct 31.

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Dual regulation of gastrointestinal tumor progression by the IFN-γ/STAT1 pathway and prospects for targeted therapy.
Front Oncol. 2025 Aug 20;15:1598170. doi: 10.3389/fonc.2025.1598170. eCollection 2025.
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Tumor-intrinsic interferon signaling drives pancreatic cancer resistance to tumor mucin1-targeted CAR T cell therapy.
Front Immunol. 2025 Aug 8;16:1618415. doi: 10.3389/fimmu.2025.1618415. eCollection 2025.
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5'-Phosphorothioester Linked Cyclic Dinucleotides, Endo-S-CDNs, Displaying Impressive Antitumor Activities In Vivo when Dosed Subcutaneously.
ACS Bio Med Chem Au. 2025 Jun 6;5(4):665-693. doi: 10.1021/acsbiomedchemau.5c00070. eCollection 2025 Aug 20.
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Chemokines: humble yet mighty players in the tumour microenvironment.
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Peripheral cytokine and monocyte phenotype associations in drug-resistant epilepsy.
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Inflammatory cytokines are associated with response and prognosis in patients with esophageal cancer.
Oncotarget. 2017 Jul 18;8(29):47518-47532. doi: 10.18632/oncotarget.17671.
2
Expansion of Tumor-Infiltrating CD8 T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy.
Cancer Res. 2017 Jul 1;77(13):3672-3684. doi: 10.1158/0008-5472.CAN-17-0236. Epub 2017 May 18.
3
COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells.
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1117-1122. doi: 10.1073/pnas.1612920114. Epub 2017 Jan 17.
4
CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer.
Br J Cancer. 2016 Aug 23;115(5):553-63. doi: 10.1038/bjc.2016.172. Epub 2016 Aug 4.
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Regular Aspirin Use Associates With Lower Risk of Colorectal Cancers With Low Numbers of Tumor-Infiltrating Lymphocytes.
Gastroenterology. 2016 Nov;151(5):879-892.e4. doi: 10.1053/j.gastro.2016.07.030. Epub 2016 Jul 27.
6
Chemoattractant Receptors BLT1 and CXCR3 Regulate Antitumor Immunity by Facilitating CD8+ T Cell Migration into Tumors.
J Immunol. 2016 Sep 1;197(5):2016-26. doi: 10.4049/jimmunol.1502376. Epub 2016 Jul 27.
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CXCR3A contributes to the invasion and metastasis of gastric cancer cells.
Oncol Rep. 2016 Sep;36(3):1686-92. doi: 10.3892/or.2016.4953. Epub 2016 Jul 19.
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Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer.
Br J Cancer. 2016 Jul 12;115(2):252-60. doi: 10.1038/bjc.2016.166. Epub 2016 Jul 5.
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CXCL11-Armed oncolytic poxvirus elicits potent antitumor immunity and shows enhanced therapeutic efficacy.
Oncoimmunology. 2015 Oct 29;5(3):e1091554. doi: 10.1080/2162402X.2015.1091554. eCollection 2016 Mar.

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