Koppad Anand K, Kaulgud Ram S, Arun B S
Assistant Professor, Department of Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
Assistant Professor, Department of Medicine, MVJ Medical College and Research Hospital, Hoskote, Karnataka, India.
J Clin Diagn Res. 2017 Sep;11(9):OC17-OC20. doi: 10.7860/JCDR/2017/25710.10609. Epub 2017 Sep 1.
It has been observed that metabolic syndrome is risk factor for Coronary Artery Disease (CAD) and exerts its effects through fat deposition and vascular aging. CAD has been acknowledged as a leading cause of death. In earlier studies, the metabolic risk has been estimated by Framingham risk score. Recent studies have shown that Neck Circumference (NC) has a good correlation with other traditional anthropometric measurements and can be used as marker of obesity. It also correlates with Framingham risk score, which is slightly more sophisticated measure of CAD risk.
To assess the risk of CAD in a subject based on NC and to correlate the NC to Framingham risk score.
The present cross-sectional study, done at Karnataka Institute of Medical Sciences, Hubli, Karnataka, India, includes 100 subjects. The study duration was of one year from 1 January 2015 to 31 December 2015. Anthropometric indices Body Mass Index (BMI) and NC were correlated with 10 year CAD risk as calculated by Framingham risk score. The correlation between BMI, NC, vascular age and Framingham risk score was calculated using Karl Pearson's correlation method.
NC has a strong correlation with 10 year CAD risk (p≤0.001). NC was significantly greater in males as compared to females (p≤0.001). Males had greater risk of cardiovascular disease as reflected by higher 10 year Framingham risk score (p≤0.0035).
NC gives simple and easy prediction of CAD risk and is more reliable than traditional risk markers like BMI. NC correlates positively with 10 year Framingham risk score.
据观察，代谢综合征是冠状动脉疾病（CAD）的危险因素，并通过脂肪沉积和血管老化发挥作用。CAD已被公认为主要死因。在早期研究中，代谢风险通过弗雷明汉风险评分来估计。最近的研究表明，颈围（NC）与其他传统人体测量指标具有良好的相关性，可作为肥胖的标志物。它还与弗雷明汉风险评分相关，后者是一种对CAD风险更为复杂的测量方法。
基于颈围评估受试者患CAD的风险，并将颈围与弗雷明汉风险评分相关联。
本横断面研究在印度卡纳塔克邦胡布利市的卡纳塔克医学科学研究所进行，纳入了100名受试者。研究持续时间为一年，从2015年1月1日至2015年12月31日。人体测量指标体重指数（BMI）和颈围与通过弗雷明汉风险评分计算的10年CAD风险相关。使用卡尔·皮尔逊相关方法计算BMI、颈围、血管年龄和弗雷明汉风险评分之间的相关性。
颈围与10年CAD风险具有强相关性（p≤0.001）。男性的颈围显著大于女性（p≤0.001）。男性患心血管疾病的风险更高，10年弗雷明汉风险评分更高即表明了这一点（p≤0.0035）。
颈围能简单且容易地预测CAD风险，比体重指数等传统风险标志物更可靠。颈围与10年弗雷明汉风险评分呈正相关。
