甲状腺激素对灌注大鼠肝脏中生长调节素-C释放的影响。
Effect of thyroid hormone on somatomedin-C release from perfused rat liver.
作者信息
Ikeda T, Fujiyama K, Takeuchi T, Honda M, Mokuda O, Tominaga M, Mashiba H
机构信息
First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
出版信息
Experientia. 1989 Feb 15;45(2):170-1. doi: 10.1007/BF01954863.
The effect of thyroid hormone on plasma somatomedin-C (SmC) level and on SmC release from perfused rat liver was investigated. Plasma SmC levels and liver tissue SmC were significantly increased in thyroxine-treated rats. Physiological doses of triiodothyronine increased SmC release and SmC concentration in the perfused rat liver. These results indicate that thyroid hormone directly enhances the synthesis and release of SmC in the rat.
研究了甲状腺激素对大鼠血浆生长调节素C（SmC）水平以及对灌注大鼠肝脏中SmC释放的影响。用甲状腺素处理的大鼠血浆SmC水平和肝脏组织SmC显著升高。生理剂量的三碘甲状腺原氨酸增加了灌注大鼠肝脏中SmC的释放和SmC浓度。这些结果表明，甲状腺激素直接增强了大鼠体内SmC的合成和释放。
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