Department of Optics, Pharmacology and Anatomy, University of Alicante, Carretera de San Vicente del Raspeig s/n, 03690 San Vicente del Raspeig, Alicante, Spain; Public Health Research Group, University of Alicante, Carretera de San Vicente del Raspeig s/n, 03690 San Vicente del Raspeig, Alicante, Spain.
Department of Optics, Pharmacology and Anatomy, University of Alicante, Carretera de San Vicente del Raspeig s/n, 03690 San Vicente del Raspeig, Alicante, Spain.
Cont Lens Anterior Eye. 2018 Apr;41(2):187-192. doi: 10.1016/j.clae.2017.11.006. Epub 2017 Dec 6.
To determine the usefulness of a silicone-hydrogel bandage contact lens (BCL) in the immediate postoperative period after uneventful myopic laser in-situ keratomileusis (LASIK).
The study design was randomized but not masked and data collection was prospective. This study comprised 51 consecutive myopic eyes intervened by means of the LASIK technique to compensate their refractive error. Patients were randomly assigned to two different groups. The experimental group included 24 eyes of 12 patients that were fitted with a BCL immediately after the flap replacement. The control group included 27 eyes of 14 patients with no BCL. Patients were examined 24h after the surgery; the experimental group was analyzed immediately after the extraction of the BCL. Postoperative uncorrected distance visual acuity (UDVA) and postoperative topographic indexes were compared to baseline in both groups.
The experimental group achieved worse results in the majority of the studied variables. Postoperative UDVA was worse in experimental group (p<0.01). Likewise, corneal asphericity (Q) was significantly higher in experimental group (p=0.024). Topographic indexes showed higher asymmetry in the corneal maps pertaining to experimental group. Specifically, the index of surface variance (ISV) (p=0.017) and index of vertical asymmetry (IVA) (p=0.031) were higher in experimental group. Also, the postoperative central corneal thickness (CCT) resulted in higher values for eyes pertaining to experimental group.
The fitting of a silicone-hydrogel BCL after uneventful LASIK provokes morphological changes in the ocular structures that may lead to a worse UDVA secondary to a higher postoperative CCT and corneal edema.
确定在无并发症的近视激光原位角膜磨镶术（LASIK）后即刻应用硅水凝胶绷带接触镜（BCL）的效果。
本研究设计为随机但非盲法，数据收集为前瞻性。本研究包括 51 例连续接受 LASIK 技术矫正近视的患者。患者随机分为两组。实验组包括 12 例 24 只眼，在瓣复位后立即佩戴 BCL。对照组包括 14 例 27 只眼，未佩戴 BCL。术后 24 小时对所有患者进行检查，实验组在 BCL 取出后立即进行分析。比较两组术后未矫正远视力（UDVA）和术后地形学指标与基线的差异。
实验组在大多数研究变量中均获得较差的结果。实验组术后 UDVA 较差（p<0.01）。同样，实验组角膜非球面性（Q）明显较高（p=0.024）。实验组角膜地形图显示更高的角膜不对称性。具体而言，实验组表面变异指数（ISV）（p=0.017）和垂直不对称指数（IVA）（p=0.031）较高。此外，实验组术后中央角膜厚度（CCT）值较高。
在无并发症的 LASIK 术后佩戴硅水凝胶 BCL 会引起眼部结构的形态变化，可能导致术后 CCT 增加和角膜水肿，从而导致 UDVA 下降。
