氨甲酰磷酸合酶（谷氨酰胺）：天冬氨酸氨甲酰转移酶：二氢乳清酸酶多酶复合物（大鼠腹水肝癌细胞和大鼠肝脏） - Suppr

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A multienzyme complex of carbamoyl-phosphate synthase (glutamine): aspartate carbamoyltransferase: dihydoorotase (rat ascites hepatoma cells and rat liver).

作者信息

Mori M, Tatibana M

出版信息

Methods Enzymol. 1978;51:111-20. doi: 10.1016/s0076-6879(78)51019-7.

DOI:10.1016/s0076-6879(78)51019-7

PMID:29209

Abstract

摘要

相似文献

A multienzyme complex of carbamoyl-phosphate synthase (glutamine): aspartate carbamoyltransferase: dihydoorotase (rat ascites hepatoma cells and rat liver).氨甲酰磷酸合酶（谷氨酰胺）：天冬氨酸氨甲酰转移酶：二氢乳清酸酶多酶复合物（大鼠腹水肝癌细胞和大鼠肝脏）

Methods Enzymol. 1978;51:111-20. doi: 10.1016/s0076-6879(78)51019-7.

Multi-enzyme complex of glutamine-dependent carbamoyl-phosphate synthetase with aspartate carbamoyltransferase and dihydroorotase from rat ascites-hepatoma cells. Purification, molecular properties and limited proteolysis.来自大鼠腹水肝癌细胞的谷氨酰胺依赖性氨甲酰磷酸合成酶与天冬氨酸氨甲酰转移酶和二氢乳清酸酶的多酶复合物。纯化、分子特性及有限蛋白酶解

Eur J Biochem. 1978 May 16;86(2):381-8. doi: 10.1111/j.1432-1033.1978.tb12320.x.

Purification of a multifunctional protein bearing carbamyl-phosphate synthase, aspartate transcarbamylase, and dihydroorotase enzyme activities from mutant hamster cells.从突变仓鼠细胞中纯化一种具有氨甲酰磷酸合成酶、天冬氨酸转氨甲酰酶和二氢乳清酸酶活性的多功能蛋白质。

Methods Enzymol. 1978;51:121-34. doi: 10.1016/s0076-6879(78)51020-3.

Purification of homogeneous glutamine-dependent carbamyl phosphate synthetase from ascites hepatoma cells as a complex with aspartate transcarbamylase and dihydroorotase.从腹水肝癌细胞中纯化出与天冬氨酸转氨甲酰酶和二氢乳清酸酶形成复合物的纯质谷氨酰胺依赖性氨甲酰磷酸合成酶。

J Biochem. 1975 Jul;78(1):239-42.

Isolation of a multifunctional complex containing the first three enzymes of pyrimidine biosynthesis in drosophila melanogaster.在黑腹果蝇中分离出一种包含嘧啶生物合成前三种酶的多功能复合物。

FEBS Lett. 1976 Nov;70(1):71-5. doi: 10.1016/0014-5793(76)80728-4.

The catalytic mechanism of hamster dihydroorotase.仓鼠二氢乳清酸酶的催化机制。

Adv Exp Med Biol. 1994;370:549-53. doi: 10.1007/978-1-4615-2584-4_116.

CAD overexpression in mammalian cells.CAD在哺乳动物细胞中的过表达。

Adv Exp Med Biol. 1998;431:481-5. doi: 10.1007/978-1-4615-5381-6_95.

Modification of the aggregation state of the multifunctional enzyme complex catalyzing the first steps in pyrimidine biosynthesis in the course of development of Drosophila melanogaster.在黑腹果蝇发育过程中，催化嘧啶生物合成第一步的多功能酶复合物聚集状态的改变。

Dev Biol. 1981 May;84(1):157-63. doi: 10.1016/0012-1606(81)90379-1.

Studies on channeling of carbamoyl-phosphate in the multienzyme complex that initiates pyrimidine biosynthesis in rat ascites hepatoma cells.对大鼠腹水肝癌细胞中启动嘧啶生物合成的多酶复合物中氨甲酰磷酸通道化的研究。

J Biochem. 1982 Nov;92(5):1431-7. doi: 10.1093/oxfordjournals.jbchem.a134067.

Reversible dissociation of a carbamoyl phosphate synthase-aspartate transcarbamoylase-dihydroorotase complex from ovarian eggs of Rana catesbeiana: effect of uridine triphosphate and other modifiers.牛蛙卵巢卵中氨甲酰磷酸合成酶-天冬氨酸转氨甲酰酶-二氢乳清酸酶复合物的可逆解离：三磷酸尿苷及其他调节剂的作用

Proc Natl Acad Sci U S A. 1975 May;72(5):1712-6. doi: 10.1073/pnas.72.5.1712.

引用本文的文献

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.生长信号通过 mTOR 和 S6K1 刺激从头合成嘧啶。

Science. 2013 Mar 15;339(6125):1323-8. doi: 10.1126/science.1228792. Epub 2013 Feb 21.

Activation of carbamoyl phosphate synthetase by cryoprotectants.冷冻保护剂对氨甲酰磷酸合成酶的激活作用。

Mol Cell Biochem. 1983;53-54(1-2):279-98. doi: 10.1007/BF00225260.

Nucleotide sequence of the pyrimidine specific carbamoyl phosphate synthetase, a part of the yeast multifunctional protein encoded by the URA2 gene.嘧啶特异性氨甲酰磷酸合成酶的核苷酸序列，它是由URA2基因编码的酵母多功能蛋白的一部分。

Mol Gen Genet. 1987 May;207(2-3):314-9. doi: 10.1007/BF00331595.

Antipain inhibits thyroxine-induced synthesis of carbamyl phosphate synthetase I in tadpole liver.抗痛素抑制蝌蚪肝脏中甲状腺素诱导的氨甲酰磷酸合成酶I的合成。

Proc Natl Acad Sci U S A. 1978 Nov;75(11):5339-43. doi: 10.1073/pnas.75.11.5339.

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